DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment flz and f7

DIOPT Version :9

Sequence 1:	NP_001137622.1	Gene:	flz / 35902	FlyBaseID:	FBgn0286782	Length:	1693	Species:	Drosophila melanogaster
Sequence 2:	NP_571894.2	Gene:	f7 / 114423	ZFINID:	ZDB-GENE-010814-1	Length:	433	Species:	Danio rerio

Alignment Length:	269	Identity:	88/269 - (32%)
Similarity:	138/269 - (51%)	Gaps:	30/269 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly  1438 CGVRPHVKSG-----------RIVGGKGSTFGAYPWQVLVRESTWLGLFTKNKCGGVLITSRYVI 1491
            ||..|.:::|           |||||.....|..|||||::..      .|..||||:....:::
Zfish   174 CGKVPLLQAGKAADHQVDLRSRIVGGSECPKGHCPWQVLLKYG------EKGFCGGVIYKPTWIL 232

  Fly  1492 TAAHCQPGFLASLVAVM-GEFDISGDLESKRSVTKNVKRVIVHRQYDPATFENDLALLELDSPVQ 1555
            |||||........:.:: ||.|:..|..:::.:  .|.::..|..|...|.::|:|||.|.:|:.
Zfish   233 TAAHCLEKLKVKFLRIVAGEHDLEVDEGTEQLI--QVDQMFTHPAYVSETADSDIALLRLRTPIV 295

  Fly  1556 FDTHIVPICMP-NDVAD---FTGRMATVTGWGRLKYGGGVPSVLQEVQVPIIENSVCQEMFHTAG 1616
            :..:.||:|:| .::|:   :.....||:|||:....|....:|:.:.||.|....|.::
Zfish   296 YSVYAVPVCLPLREMAERELWAVSKHTVSGWGKRSEDGPTSRLLRRLLVPRIRTQECVQV----- 355

  Fly  1617 HNKKILTSFLCAGYANGQKDSCEGDSGGPLVLQRPDGRYELAGTVSHGIKCAAPYLPGVYMRTTF 1681
            .|..:.::..||||..|::|||:||||||||.:..|..: |.|.||.|..||.|...|:|.|.:.
Zfish   356 SNLTLTSNMFCAGYIEGRQDSCKGDSGGPLVTRYRDTAF-LLGIVSWGKGCARPGSYGIYTRVSN 419

  Fly  1682 YKPWLRSIT 1690
            |..|:|..|
Zfish   420 YLQWIRQTT 428

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
flz	NP_001137622.1	PRK14948	<272..452	CDD:237862
		PRK11633	<365..>439	CDD:236940
		PRK10263	<547..>1005	CDD:236669
		PHA03247	<792..1096	CDD:223021
		Tryp_SPc	1449..1689	CDD:238113	82/244 (34%)
f7	NP_571894.2	GLA	19..82	CDD:214503
		EGF_CA	86..121	CDD:238011
		FXa_inhibition	131..166	CDD:291342
		Tryp_SPc	195..424	CDD:214473	81/242 (33%)
		Tryp_SPc	196..427	CDD:238113	82/244 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910