Protein Alignment flz and KLK8

DIOPT Version :10

• Sequence 1: NP_001137622.1
• Gene: flz / 35902
• FlyBaseID: FBgn0286782
• Length: 1693
• Species: Drosophila melanogaster
• Sequence 2: NP_653088.1
• Gene: KLK8 / 11202
• HGNCID: 6369
• Length: 305
• Species: Homo sapiens
• Alignment Length: 282
• Identity: 85/282 - (30%)
• Similarity: 123/282 - (43%)
• Gaps: 47/282 - (16%)

  Fly  1422 RTLPTPNLAFHSPSTECGVRPHVKSGRIVGGKGSTFGAYPWQVLVRESTWLGLFTKNKCGGVLIT 1486
            |:.|.|..|.||.:.|         .:::||......:.|||..:.:...|      .|||||:.
Human    60 RSNPLPPAAGHSRAQE---------DKVLGGHECQPHSQPWQAALFQGQQL------LCGGVLVG 109

  Fly  1487 SRYVITAAHC-QPGFLASLVAVMGEFDISGD--LESKRSVTKNVKRV--IVHRQYDPATFE---N 1543
            ..:|:||||| :|.:...|          ||  |::|....:.:..|  |.|..|:.:..|   :
Human   110 GNWVLTAAHCKKPKYTVRL----------GDHSLQNKDGPEQEIPVVQSIPHPCYNSSDVEDHNH 164

  Fly  1544 DLALLELDSPVQFDTHIVPICMPNDVADFTGRMATVTGWGRL-KYGGGVPSVLQEVQVPIIENSV 1607
            ||.||:|.......:.:.||.:. |.....|:..||:|||.: ......|..|...:|.|.....
Human   165 DLMLLQLRDQASLGSKVKPISLA-DHCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKK 228

  Fly  1608 CQEMFHTAGHNKKILTSFLCAGYANGQKDSCEGDSGGPLVLQRPDGRYELAGTVSHGI-KCAAPY 1671
            |::     .:..:|....:|||.:.| .|:|:||||||||.   ||  .|.|..|.|. .|....
Human   229 CED-----AYPGQITDGMVCAGSSKG-ADTCQGDSGGPLVC---DG--ALQGITSWGSDPCGRSD 282

  Fly  1672 LPGVYMRTTFYKPWLRSITGVK 1693
            .||||.....|..|::.|.|.|
Human   283 KPGVYTNICRYLDWIKKIIGSK 304

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
flz	NP_001137622.1	PRK11633	<365..>439	CDD:236940
		PRK10263	<547..>1005	CDD:236669
		PHA03247	<792..1096	CDD:223021
		Tryp_SPc	1449..1689	CDD:238113	75/249 (30%)
KLK8	NP_653088.1	Tryp_SPc	77..297	CDD:214473	74/247 (30%)