DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment flz and f12

DIOPT Version :10

Sequence 1:NP_001137622.1 Gene:flz / 35902 FlyBaseID:FBgn0286782 Length:1693 Species:Drosophila melanogaster
Sequence 2:XP_017947702.2 Gene:f12 / 100493769 XenbaseID:XB-GENE-1004811 Length:597 Species:Xenopus tropicalis


Alignment Length:354 Identity:110/354 - (31%)
Similarity:160/354 - (45%) Gaps:75/354 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly  1349 TTTRRPATKKPTRRVSSTVKTTTVSSARPADDEIVDEEDEEDVNPNPSDNEIDQGATLSSYGGAN 1413
            ||.....||.|:...||....:|.|   |::|           ...|.|..||.....       
 Frog   302 TTAPPKVTKTPSPTKSSNHSASTPS---PSND-----------TQGPVDGRIDLPVDC------- 345

  Fly  1414 GRKIHSTSRTLPTPNLAFHSPSTECGVRPHVKSGRIVGGKGSTFGAYPWQVLVRESTWLGLFTKN 1478
            |||...|...:|                      |||||..:...::|:..        .|:..|
 Frog   346 GRKFQKTPSIMP----------------------RIVGGLVALPASHPYIA--------ALYIDN 380

  Fly  1479 K-CGGVLITSRYVITAAHC--QPGFLASLVAVMGE--FDISGDLESKRSVTKNVKRVIVHRQYDP 1538
            . |||.||:..:::|||||  |...:..:..|:|:  |:.:    .:.:||..|::.|:|.:|..
 Frog   381 HFCGGSLISPCWIVTAAHCLDQRPNVTKISVVLGQSRFNTT----DQHTVTLLVEKYILHEKYYG 441

  Fly  1539 ATFENDLALLELDS-----PVQFDTHIVPICMPND--VADFTGRMATVTGWGRLKYGGG--VPSV 1594
            .|.::|:||:::.|     ..:|...:.|||:|..  :|:.| :...|.|||. :|.|.  ....
 Frog   442 DTLQHDIALVKVKSINGLCASEFSQFVQPICLPQQFKMAEST-KQCVVAGWGH-QYEGAEHYAFF 504

  Fly  1595 LQEVQVPIIENSVCQEMFHTAGHNKKILTSFLCAGYANGQKDSCEGDSGGPLVLQRPDGRYELAG 1659
            |||..:|||..:.||.   .:.|..::|...||||:..|..|:|:||||||||.: .|||.||.|
 Frog   505 LQEASMPIIPYTQCQS---PSVHGDRMLPGMLCAGFMEGGVDACQGDSGGPLVCE-VDGRIELHG 565

  Fly  1660 TVSHGIKCAAPYLPGVYMRTTFYKPWLRS 1688
            .||.|..||....||||...|.|..|:|:
 Frog   566 VVSWGSGCAEENKPGVYTAVTSYTDWIRA 594

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
flzNP_001137622.1 PRK11633 <365..>439 CDD:236940
PRK10263 <547..>1005 CDD:236669
PHA03247 <792..1096 CDD:223021
Tryp_SPc 1449..1689 CDD:238113 89/254 (35%)
f12XP_017947702.2 FN2 40..87 CDD:238019
EGF_CA 95..129 CDD:238011
KR 213..298 CDD:214527
Tryp_SPc 359..595 CDD:238113 89/254 (35%)
Blue background indicates that the domain is not in the aligned region.

Return to query results.
Submit another query.