DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment flz and tmprss3a

DIOPT Version :9

Sequence 1:	NP_001137622.1	Gene:	flz / 35902	FlyBaseID:	FBgn0286782	Length:	1693	Species:	Drosophila melanogaster
Sequence 2:	XP_021334565.1	Gene:	tmprss3a / 100000148	ZFINID:	ZDB-GENE-070912-70	Length:	543	Species:	Danio rerio

Alignment Length:	285	Identity:	102/285 - (35%)
Similarity:	146/285 - (51%)	Gaps:	37/285 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly  1416 KIH---STSRTLPTPNLAFHSPSTECGVRPHVKSGRIVGGKGSTFGAYPWQVLVRESTWLGLFTK 1477
            |||   ::|:|..:..:........||.||.. |.|||||..|..|.:||||        .|..:
Zfish   263 KIHNITNSSKTKCSLGMVTALKCIACGSRPKF-SARIVGGNLSAEGQFPWQV--------SLHFQ 318

  Fly  1478 NK--CGGVLITSRYVITAAHCQPGFLASLVAVMGEFDISGDLESKRSVTK--NVKRVIVHRQYDP 1538
            |:  |||.:||||:::|||||..|....:..::    .:|..|...:..|  .|:::|.|.:|.|
Zfish   319 NEHLCGGSIITSRWILTAAHCVYGIAYPMYWMV----YAGLTELPLNAVKAFAVEKIIYHSRYRP 379

  Fly  1539 ATFENDLALLELDSPVQFDTHIVPICMPNDVADF-TGRMATVTGWGRLKYGGGVPSVLQE-VQVP 1601
            ...::|:||::|..|:.|:..:.|||:||....| .|:|..::|||..:.||.. ||.|. ..||
Zfish   380 KGLDHDIALMKLAQPLTFNGMVEPICLPNFGEQFEDGKMCWISGWGATEDGGDA-SVSQHCASVP 443

  Fly  1602 IIENSVCQEM-----FHTAGHNKKILTSFLCAGYANGQKDSCEGDSGGPLVLQRPDGRYELAGTV 1661
            :|.|..|.:.     :.|||        .:||||.:|..|||:|||||||..: ....::|.|..
Zfish   444 LISNKACSQPEVYQGYLTAG--------MICAGYLDGGTDSCQGDSGGPLACE-DSSIWKLVGAT 499

  Fly  1662 SHGIKCAAPYLPGVYMRTTFYKPWL 1686
            |.|..||....||||.|.|....|:
Zfish   500 SWGQGCAEKNKPGVYTRITQSLTWI 524

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
flz	NP_001137622.1	PRK14948	<272..452	CDD:237862
		PRK11633	<365..>439	CDD:236940
		PRK10263	<547..>1005	CDD:236669
		PHA03247	<792..1096	CDD:223021
		Tryp_SPc	1449..1689	CDD:238113	91/249 (37%)
tmprss3a	XP_021334565.1	LDLa	154..186	CDD:238060
		SRCR_2	191..292	CDD:317845	7/28 (25%)
		Tryp_SPc	298..525	CDD:238113	91/249 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910