Protein Alignment babo and tgfbr1b

DIOPT Version :10

• Sequence 1: NP_476999.1
• Gene: babo / 35900
• FlyBaseID: FBgn0011300
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: NP_001108531.1
• Gene: tgfbr1b / 792928
• ZFINID: ZDB-GENE-091027-1
• Length: 505
• Species: Danio rerio
• Alignment Length: 498
• Identity: 281/498 - (56%)
• Similarity: 351/498 - (70%)
• Gaps: 30/498 - (6%)

  Fly   127 IKCHCDTCKESNNICETDGFCFTSVEKNSDGSIIFSYR-CLHKSQIFPPGRSIWCNDGLHGGPTA 190
            ::|:|..|  .|:.|.|||.|:.|:.:  .||:..... |:.|.::.||.|...|      .|:.
Zfish    34 LQCYCHRC--PNHTCTTDGLCYVSITR--AGSLTTQQSWCIGKGELVPPDRPFVC------APST 88

  Fly   191 RPVGRNGAHACCKDRDFCNRFLWPKTKDQRSDRVEEGRQISVQDYVPHRLTSWEFVAIILGATLF 255
            :  ..:|.:..|.|.|:||       ||      .:.:...|....|..|....|.|:|.|....
Zfish    89 K--DDSGIYPLCCDTDWCN-------KD------PDIKAFPVPTQKPPALGPVAFAALIAGPVCV 138

  Fly   256 ICFTGTSTWYYCQRRKRMASGRTFAKEDSAYD-PILNGNTTIHDII-EMTTSGSGSAGLPLLVQR 318
            :||...:.:|.|..|. :...|..::||.:.| |.:...||:.|:| :|||||||| ||||||||
Zfish   139 LCFLMVTVFYICHSRS-VIHHRVPSEEDPSLDHPFITVGTTLKDLIYDMTTSGSGS-GLPLLVQR 201

  Fly   319 SIARQVQLCHVIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGFIA 383
            :|||.:.|...|||||||||||||||||.|||||||||||.||||||||||||||||||||||||
Zfish   202 TIARTIILQESIGKGRFGEVWRGRWRGEEVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIA 266

  Fly   384 ADNKDNGTWTQLWLVTDYHENGSLFDYLTTHPVDTNTMLNMSLSIATGLAHLHMDIVGTRGKPAI 448
            |||||||||||||||:||||:|||||||..:.|....|:.:|||.|:|||||||:||||:|||||
Zfish   267 ADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLSLSTASGLAHLHMEIVGTQGKPAI 331

  Fly   449 AHRDLKSKNILVKSNLSCAIGDLGLAVRHVEKNDSVDIPSTHRVGTKRYMAPEVLDESMNDQHFD 513
            |||||||||||||.|.:|.|.||||||||....|::||...|||||||||||||||:|:|.:||:
Zfish   332 AHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPNHRVGTKRYMAPEVLDDSINMKHFE 396

  Fly   514 SYKRADVYAFGLILWEIARRCNMGMIYDEYQLPYYDVVQPDPSIEEMKKVVCIEKCRPNIPNRWH 578
            |:||||:||.||:.||||.||::|.|:::|||||:|:||.|||:|||::|||.:|.||||||||.
Zfish   397 SFKRADIYAMGLVFWEIASRCSIGGIHEDYQLPYHDLVQSDPSVEEMRRVVCEQKLRPNIPNRWQ 461

  Fly   579 ASDVLHNMAKVMKECWYPNPVARLTALRIKKTLASISVEDKVK 621
            :.:.|..|||:|:||||.|..||||||||||||:.:|.::.:|
Zfish   462 SCEALRVMAKIMRECWYANGAARLTALRIKKTLSQLSQQEGIK 504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
babo	NP_476999.1	TFP_LU_ECD_Babo	127..210	CDD:467127	24/83 (29%)
		GS	294..324	CDD:197743	23/30 (77%)
		STKc_TGFbR1_ACVR1b_ACVR1c	328..615	CDD:271045	211/286 (74%)
tgfbr1b	NP_001108531.1	TFP_LU_ECD_ALK5	34..106	CDD:467067	25/90 (28%)
		TGF_beta_GS	178..205	CDD:462503	20/27 (74%)
		STKc_TGFbR1_ACVR1b_ACVR1c	211..498	CDD:271045	211/286 (74%)