Protein Alignment babo and BMPR1A

DIOPT Version :10

• Sequence 1: NP_476999.1
• Gene: babo / 35900
• FlyBaseID: FBgn0011300
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: NP_001393488.1
• Gene: BMPR1A / 657
• HGNCID: 1076
• Length: 557
• Species: Homo sapiens
• Alignment Length: 260
• Identity: 52/260 - (20%)
• Similarity: 86/260 - (33%)
• Gaps: 90/260 - (34%)

  Fly    97 RVPQTLPKMTKLKFLSITQCKI---TVLRLDMFADNQY---LKNLD-LSYNQIQQL--LPVTGRP 152
            |..:|||...|:..|.    ::   ||:.:....|..|   |:|.. :..||:.:.  |...||.
Human   124 RCNKTLPVAFKVVALG----EVPDGTVVTVMAGNDENYSAELRNASAVMKNQVARFNDLRFVGRS 184

  Fly   153 ARMLSIETLTLRGNLLQNLDLALFVAMPQLLNLNFLNNLIV-----------SLDVSAPIALPNL 206
            .|..|. |||          :.:|...||:...:....:.|           .||.|.|
Human   185 GRGKSF-TLT----------ITVFTNPPQVATYHRAIKVTVDGPREPRRHRQKLDDSKP------ 232

  Fly   207 SGLYLGYNKLVSLDLRNLTLPKLETFSFGPNALTQMPILPR-PLPKFNYLSLSANNLTQLDMT-- 268
                            :|...:|......|:...::.:.|: |.|..|......|...|..:|
Human   233 ----------------SLFSDRLSDLGRIPHPSMRVGVPPQNPRPSLNSAPSPFNPQGQSQITDP 281

  Fly   269 ----------YFRPYPNLQKIYISSNQITTVRASSPVRLQVDYLELSNNKITTFNITGWDMPNIT 323
                      |.:.||:    |:|.....::.:::|         ||:.:       |..:|.||
Human   282 RQAQSSPPWSYDQSYPS----YLSQMTSPSIHSTTP---------LSSTR-------GTGLPAIT 326

  Fly   324  323
            Human   327  326

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
babo	NP_476999.1	TFP_LU_ECD_Babo	127..210	CDD:467127	22/99 (22%)
		GS	294..324	CDD:197743	7/30 (23%)
		STKc_TGFbR1_ACVR1b_ACVR1c	328..615	CDD:271045
BMPR1A	NP_001393488.1	TFP_LU_ECD_BMPR1A	57..140	CDD:467132	6/19 (32%)
		TGF_beta_GS	230..257	CDD:462503	5/48 (10%)
		STKc_BMPR1a	263..549	CDD:271122	16/84 (19%)