DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment babo and Pomk

DIOPT Version :9

Sequence 1:	NP_476999.1	Gene:	babo / 35900	FlyBaseID:	FBgn0011300	Length:	622	Species:	Drosophila melanogaster
Sequence 2:	NP_001020054.1	Gene:	Pomk / 306549	RGDID:	1310810	Length:	349	Species:	Rattus norvegicus

Alignment Length:	294	Identity:	69/294 - (23%)
Similarity:	119/294 - (40%)	Gaps:	68/294 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   318 RSIARQVQLCHVIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVML-----RH-E 376
            |:..||::|   :|:|....|:...|....||:...:..|    .:|..::...||     :| .
  Rat    77 RTEVRQLKL---VGEGAVKRVFLSEWNEHKVALSRLTRLE----MKEDFLHGLRMLTSLQSQHVV 134

  Fly   377 NILGFIAADNKDNGTWTQLWLVTDYHENGSLFDYLTTHPV----DTNT---MLNMSLSIATGLAH 434
            .:.||.    :::||     ::|:||..|||.:...|..:    |.||   .|.:::...:.:.:
  Rat   135 TLAGFC----EEDGT-----ILTEYHPLGSLSNLEETLNLSKYRDVNTWQHRLRLAVEYVSIINY 190

  Fly   435 LHMDIVGTRGKPAIAHRDLKS--KNILVKSNLSCAIGDLGLAVRHVEKNDSVDIPSTHRVGTKRY 497
            ||...:|||  ......||..  ...|:.||.|....||. |:..|:....|.:...||.....:
  Rat   191 LHHSPLGTR--VMCDSNDLPKTLSQYLLTSNFSIVANDLD-ALPLVDHGSRVLVKCGHRELHGDF 252

  Fly   498 MAPEVL----------DESM--NDQHFDSYKRADVYAFGL-----------ILWEIARRCNMGM- 538
            :|||.|          |:.|  .|:..|.:|..||.:|.|           .|::|.:.|....
  Rat   253 VAPEQLWPYGEDTPFQDDLMPPYDEKIDIWKIPDVSSFLLGHVEGSDMVRFHLFDIHKACKNQFP 317

  Fly   539 --------IYDEYQLPYYDVVQPDPSIEEMKKVV 564
                    :.|.||..::.:  .|..:.:.|:::
  Rat   318 AERPTAQNVLDAYQKVFHSL--RDTVMSQTKEML 349

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
babo	NP_476999.1	Activin_recp	127..214	CDD:279413
		GS	294..324	CDD:197743	2/5 (40%)
		Pkinase_Tyr	324..611	CDD:285015	66/288 (23%)
		STKc_TGFbR1_ACVR1b_ACVR1c	328..615	CDD:271045	65/284 (23%)
Pomk	NP_001020054.1	PKc_like	104..>194	CDD:419665	24/102 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000