Protein Alignment babo and Acvr1b

DIOPT Version :10

• Sequence 1: NP_476999.1
• Gene: babo / 35900
• FlyBaseID: FBgn0011300
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: NP_954700.1
• Gene: Acvr1b / 29381
• RGDID: 735207
• Length: 505
• Species: Rattus norvegicus
• Alignment Length: 542
• Identity: 283/542 - (52%)
• Similarity: 355/542 - (65%)
• Gaps: 58/542 - (10%)

  Fly    99 ASGAVAPAVTPQLPIYIAQPSAKKPE--NKIKCHCDTCKESNNICETDGFCFTSVEKNSDGSIIF 161
            |..|.|.:..|.:.:.:|......|.  ..:.|.|.:|.::|..|||||.|..|: .|.||....
  Rat     2 AESAGASSFFPLVVLLLAGSGGSGPRGIQALLCACTSCLQTNYTCETDGACMVSI-FNLDGMEHH 65

  Fly   162 SYRCLHKSQIFPPGRSIWC--NDGLHGGPTARPVGRNGAHACCKDRDFCNRFLWPKTKDQR--SD 222
            ...|:.|.::.|.|:..:|  ::.|          || .|.|.  .||||:.      |.|  |.
  Rat    66 VRTCIPKVELVPAGKPFYCLSSEDL----------RN-THCCY--IDFCNKI------DLRVPSG 111

  Fly   223 RVEEGRQISVQDYVPHRLTSW---EFVAIILGAT---------LFICFTGTSTWYYCQRRKRMAS 275
            .::|          |...:.|   |.|.||.|..         :|:........|:.::|..|
  Rat   112 HLKE----------PEHPSMWGPVELVGIIAGPVFLLFLIIIIVFLVINYHQRVYHNRQRLDM-- 164

  Fly   276 GRTFAKEDSAYDPILNGNTTIHDII-EMTTSGSGSAGLPLLVQRSIARQVQLCHVIGKGRFGEVW 339
                  ||.:.:..|:.:.|:.|:: :::|||||| ||||.|||::||.:.|..:||||||||||
  Rat   165 ------EDPSCEMCLSKDKTLQDLVYDLSTSGSGS-GLPLFVQRTVARTIVLQEIIGKGRFGEVW 222

  Fly   340 RGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVTDYHEN 404
            ||||||.:|||||||||||.|||||||||||||||||||||||||||||||||||||||:||||:
  Rat   223 RGRWRGGDVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEH 287

  Fly   405 GSLFDYLTTHPVDTNTMLNMSLSIATGLAHLHMDIVGTRGKPAIAHRDLKSKNILVKSNLSCAIG 469
            |||||||..:.|....|:.::||.|:|||||||:||||:|||.||||||||||||||.|..|||.
  Rat   288 GSLFDYLNRYTVTIEGMIKLALSAASGLAHLHMEIVGTQGKPGIAHRDLKSKNILVKKNGMCAIA 352

  Fly   470 DLGLAVRHVEKNDSVDIPSTHRVGTKRYMAPEVLDESMNDQHFDSYKRADVYAFGLILWEIARRC 534
            ||||||||....|::||....|||||||||||||||::|.:||||:|.||:||.||:.|||||||
  Rat   353 DLGLAVRHDAVTDTIDIAPNQRVGTKRYMAPEVLDETINMKHFDSFKCADIYALGLVYWEIARRC 417

  Fly   535 NMGMIYDEYQLPYYDVVQPDPSIEEMKKVVCIEKCRPNIPNRWHASDVLHNMAKVMKECWYPNPV 599
            |.|.:::||||||||:|..|||||||:||||.:|.|||:||.|.:.:.|..|.|:|:||||.|..
  Rat   418 NSGGVHEEYQLPYYDLVPSDPSIEEMRKVVCDQKLRPNVPNWWQSYEALRVMGKMMRECWYANGA 482

  Fly   600 ARLTALRIKKTLASISVEDKVK 621
            ||||||||||||:.:||::.||
  Rat   483 ARLTALRIKKTLSQLSVQEDVK 504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
babo	NP_476999.1	TFP_LU_ECD_Babo	127..210	CDD:467127	27/84 (32%)
		GS	294..324	CDD:197743	17/30 (57%)
		STKc_TGFbR1_ACVR1b_ACVR1c	328..615	CDD:271045	209/286 (73%)
Acvr1b	NP_954700.1	TFP_LU_ECD_ALK4	30..102	CDD:467066	26/85 (31%)
		GS	177..207	CDD:197743	17/30 (57%)
		STKc_TGFbR1_ACVR1b_ACVR1c	211..498	CDD:271045	209/286 (73%)