Protein Alignment babo and Acvr2b

DIOPT Version :10

• Sequence 1: NP_476999.1
• Gene: babo / 35900
• FlyBaseID: FBgn0011300
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: XP_038936802.1
• Gene: Acvr2b / 25366
• RGDID: 2028
• Length: 545
• Species: Rattus norvegicus
• Alignment Length: 442
• Identity: 146/442 - (33%)
• Similarity: 233/442 - (52%)
• Gaps: 66/442 - (14%)

  Fly   201 CCKDRDFCNRFLWPKTKDQRSDRVEE--GRQISVQ--DYVPHRLTSWEFVAIILGATLFICFTGT 261
            ||.:.:|||         :|...:.|  |.:::.:  ...|..||...:..:.:|....|..  .
  Rat   111 CCCEGNFCN---------ERFTHLPEPGGPEVTYEPPPTAPTLLTVLAYSLLPIGGLSLIVL--L 164

  Fly   262 STWYYCQRRKRMASGRTFAKEDSAYDPILNGNTTIHDIIEMTTSGSGSAGL-------------- 312
            :.|.|..|:...                  |:..||::.:....|.|..|.
  Rat   165 AFWMYRHRKPPY------------------GHVDIHEVRQCQRGGGGRDGCADSFKLLLFQDPGP 211

  Fly   313 ----PLLVQRSIARQVQLCHVIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVML 373
                ||:.    .:.:||..:..:||||.||:.:...:.||||||..:::.||..|.||:.|..:
  Rat   212 PPPSPLVG----LKPLQLLEIKARGRFGCVWKAQLMNDFVAVKIFPLQDKQSWQSEREIFSTPGM 272

  Fly   374 RHENILGFIAADNKDNGTWTQLWLVTDYHENGSLFDYLTTHPVDTNTMLNMSLSIATGLAHLHMD 438
            :|||:|.||||:.:.:....:|||:|.:|:.|||.|||..:.:..|.:.:::.:::.||::||.|
  Rat   273 KHENLLQFIAAEKRGSNLEVELWLITAFHDKGSLTDYLKGNIITWNELCHVAETMSRGLSYLHED 337

  Fly   439 IVGTRG---KPAIAHRDLKSKNILVKSNLSCAIGDLGLAVRHVEKNDSVDIPSTH-RVGTKRYMA 499
            :...||   ||:|||||.||||:|:||:|:..:.|.|||||........|   || :|||:||||
  Rat   338 VPWCRGEGHKPSIAHRDFKSKNVLLKSDLTAVLADFGLAVRFEPGKPPGD---THGQVGTRRYMA 399

  Fly   500 PEVLDESMNDQHFDSYKRADVYAFGLILWEIARRCNM--GMIYDEYQLPYYDVVQPDPSIEEMKK 562
            ||||:.::|.|. |::.|.|:||.||:|||:..||..  |.: |||.||:.:.:...||:||:::
  Rat   400 PEVLEGAINFQR-DAFLRIDMYAMGLVLWELVSRCKAADGPV-DEYMLPFEEEIGQHPSLEELQE 462

  Fly   563 VVCIEKCRPNIPNRWHASDVLHNMAKVMKECWYPNPVARLTALRIKKTLASI 614
            ||..:|.||.|.:.|.....|..:...::|||..:..|||:|..:::.::.|
  Rat   463 VVVHKKMRPTIKDHWLKHPGLAQLCVTIEECWDHDAEARLSAGCVEERVSLI 514

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
babo	NP_476999.1	TFP_LU_ECD_Babo	127..210	CDD:467127	4/8 (50%)
		GS	294..324	CDD:197743	7/47 (15%)
		STKc_TGFbR1_ACVR1b_ACVR1c	328..615	CDD:271045	120/293 (41%)
Acvr2b	XP_038936802.1	TFP_LU_ECD_ACVR2B	35..125	CDD:467152	6/22 (27%)
		STKc_ACVR2b	227..517	CDD:271042	120/293 (41%)