Protein Alignment babo and Tgfbr1

DIOPT Version :10

• Sequence 1: NP_476999.1
• Gene: babo / 35900
• FlyBaseID: FBgn0011300
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: XP_036019848.1
• Gene: Tgfbr1 / 21812
• MGIID: 98728
• Length: 544
• Species: Mus musculus
• Alignment Length: 585
• Identity: 297/585 - (50%)
• Similarity: 370/585 - (63%)
• Gaps: 68/585 - (11%)

  Fly    52 KAPALR---------APAGTAGHAYQSPSSSLAADNRSHDNNNASAVSMLLPQDGDASGAVAPAV 107
            :|||.|         :|.|..|...|.|.....||.....|:.
Mouse    12 RAPAWRRSGAGRLEGSPEGRKGRRGQRPRVGRTADEYGSLNSK---------------------- 54

  Fly   108 TPQLPIYIAQPSAKKPE-NKIKCHCDTCKESNNICETDGFCFTSVEKNSDGSIIFSYRCLHKSQI 171
                .:|..:..:.|.. :.::|.|..|.:.|..|||||.||.||.:.:| .:|.:..|:.:..:
Mouse    55 ----KLYFLRGRSNKVSISALQCFCHLCTKDNFTCETDGLCFVSVTETTD-KVIHNSMCIAEIDL 114

  Fly   172 FPPGRSIWCNDGLHGGPTARPVGRNGAHA---CCKDRDFCNRFLWPKTKDQRSDRVEEGRQISVQ 233
            .|..|...|          .|..:.||..   || ::|.||:...| |....|::...|
Mouse   115 IPRDRPFVC----------APSSKTGAVTTTYCC-NQDHCNKIELP-TTGPFSEKQSAG------ 161

  Fly   234 DYVPHRLTSWEFVAIILGATLFICFTGTSTWYYCQRRKRMASGRTFAKEDSAYD-PILNGNTTIH 297
                  |...|..|:|.|...|:|.......|.|..| .:...|...:||.:.| |.::..||:.
Mouse   162 ------LGPVELAAVIAGPVCFVCIALMLMVYICHNR-TVIHHRVPNEEDPSLDRPFISEGTTLK 219

  Fly   298 DII-EMTTSGSGSAGLPLLVQRSIARQVQLCHVIGKGRFGEVWRGRWRGENVAVKIFSSREECSW 361
            |:| :|||||||| ||||||||:|||.:.|...||||||||||||:||||.|||||||||||.||
Mouse   220 DLIYDMTTSGSGS-GLPLLVQRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSW 283

  Fly   362 FREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVTDYHENGSLFDYLTTHPVDTNTMLNMSL 426
            |||||||||||||||||||||||||||||||||||||:||||:|||||||..:.|....|:.::|
Mouse   284 FREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLAL 348

  Fly   427 SIATGLAHLHMDIVGTRGKPAIAHRDLKSKNILVKSNLSCAIGDLGLAVRHVEKNDSVDIPSTHR 491
            |.|:|||||||:||||:||||||||||||||||||.|.:|.|.||||||||....|::||...||
Mouse   349 STASGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPNHR 413

  Fly   492 VGTKRYMAPEVLDESMNDQHFDSYKRADVYAFGLILWEIARRCNMGMIYDEYQLPYYDVVQPDPS 556
            |||||||||||||:|:|.:||:|:||||:||.||:.|||||||::|.|:::|||||||:|..|||
Mouse   414 VGTKRYMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARRCSIGGIHEDYQLPYYDLVPSDPS 478

  Fly   557 IEEMKKVVCIEKCRPNIPNRWHASDVLHNMAKVMKECWYPNPVARLTALRIKKTLASISVEDKVK 621
            :|||:||||.:|.||||||||.:.:.|..|||:|:||||.|..||||||||||||:.:|.::.:|
Mouse   479 VEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQLSQQEGIK 543

  Fly   622  621
            Mouse   544  543

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
babo	NP_476999.1	TFP_LU_ECD_Babo	127..210	CDD:467127	26/85 (31%)
		GS	294..324	CDD:197743	23/30 (77%)
		STKc_TGFbR1_ACVR1b_ACVR1c	328..615	CDD:271045	211/286 (74%)
Tgfbr1	XP_036019848.1	TFP_LU_ECD_ALK5	71..145	CDD:467067	26/85 (31%)
		TGF_beta_GS	217..244	CDD:462503	20/27 (74%)
		STKc_TGFbR1_ACVR1b_ACVR1c	250..537	CDD:271045	211/286 (74%)