Protein Alignment babo and daf-1

DIOPT Version :9

• Sequence 1: NP_476999.1
• Gene: babo / 35900
• FlyBaseID: FBgn0011300
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: NP_001023159.1
• Gene: daf-1 / 176829
• WormBaseID: WBGene00000897
• Length: 669
• Species: Caenorhabditis elegans
• Alignment Length: 590
• Identity: 180/590 - (30%)
• Similarity: 272/590 - (46%)
• Gaps: 132/590 - (22%)

  Fly   129 CHCDT---CKES-------------------NNICETDGFCFTSVEKNSDGSIIFSYRCLHKSQI 171
            |||..   |...                   .|.|.|||.|:.|...:.:   |..:.|:.:..:
 Worm    56 CHCSREVGCNARTTGWVPGIEFLNETDRSFYENTCYTDGSCYQSARPSPE---ISHFGCMDEKSV 117

  Fly   172 FPPGRSIWCNDGLHGGPTARPVGRNGA---HA----CCKDRDFCNRFLWPKTKDQRSDRVEEGRQ 229
                     .|......||..|..|..   ||    ||...:||        .::....:..|
 Worm   118 ---------TDETEFHDTAAKVCTNNTKDPHATVWICCDKGNFC--------ANETIIHLAPG-- 163

  Fly   230 ISVQDYVPHRLTSWEFVAI--------ILGATLFI---CFTGTSTWYYCQRRK------------ 271
                   |.:.::|..:.|        :||..:|:   .:.....||...:.|
 Worm   164 -------PQQSSTWLILTILALLTFIVLLGIAIFLTRKSWEAKFDWYIRFKPKPGDPLRETENNV 221

  Fly   272 ---RMASGRTFAKEDSAYDPILNGNTTIH--------------------DIIEMTTSGSGSAGLP 313
               .|..|...:..:.|  ||....:|:.                    |::| .||||| .|..
 Worm   222 PMVTMGDGAGSSVPEVA--PIEQQGSTMSTSAGNSFPPGIMPNNMKDMLDVLE-ETSGSG-MGPT 282

  Fly   314 LLVQRSIARQVQLCHVIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENI 378
            .|.:.:|..|::|...:|.||||.|.||.:|||.||||:|::.:|.::.:|.||::|.||||.|:
 Worm   283 TLHKLTIGGQIRLTGRVGSGRFGNVSRGDYRGEAVAVKVFNALDEPAFHKETEIFETRMLRHPNV 347

  Fly   379 LGFIAADNKDNGTWTQLWLVTDYHENGSLFDYLTTHPVDTNTMLNMSLSIATGLAHLHMDIVGTR 443
            |.:|.:|..|.|..|:|||||:||.:|||.|:|..:.|:..|..|:..|.|:|||.||..|.|::
 Worm   348 LRYIGSDRVDTGFVTELWLVTEYHPSGSLHDFLLENTVNIETYYNLMRSTASGLAFLHNQIGGSK 412

  Fly   444 --GKPAIAHRDLKSKNILVKSNLSCAIGDLGLAVRHVEKNDSVDIPS-THRVGTKRYMAPEVLDE 505
              .|||:||||:|||||:||::|:||||||||::...|...|..|.: .::.||.||:|||:|:.
 Worm   413 ESNKPAMAHRDIKSKNIMVKNDLTCAIGDLGLSLSKPEDAASDIIANENYKCGTVRYLAPEILNS 477

  Fly   506 SMNDQHFDSYKRADVYAFGLILWEIARRCNMGMIYDEYQ---LPYYDVVQPDPSIEEMKKVVCIE 567
            :|....|:||:.||||:|.|::||...||..|.:.....   :||.:....||...:|..|||..
 Worm   478 TMQFTVFESYQCADVYSFSLVMWETLCRCEDGDVLPREAATVIPYIEWTDRDPQDAQMFDVVCTR 542

  Fly   568 KCRPNIPNRWHASDVLHNMAKVMKECWYPNPVARLTALRIKKTL------------------ASI 614
            :.||.....|.....:.::.:::|.||..||.||.|:...:|.:                  |.:
 Worm   543 RLRPTENPLWKDHPEMKHIMEIIKTCWNGNPSARFTSYICRKRMDERQQLLLDKKAKAVAQTAGV 607

  Fly   615 SVEDK 619
            :|:|:
 Worm   608 TVQDR 612

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
babo	NP_476999.1	Activin_recp	127..214	CDD:279413	24/113 (21%)
		GS	294..324	CDD:197743	11/49 (22%)
		Pkinase_Tyr	324..611	CDD:285015	126/292 (43%)
		STKc_TGFbR1_ACVR1b_ACVR1c	328..615	CDD:271045	126/310 (41%)
daf-1	NP_001023159.1	GS	265..293	CDD:197743	10/29 (34%)
		Pkinase_Tyr	293..576	CDD:285015	122/282 (43%)
		STKc_TGFbR_I	297..589	CDD:270958	125/291 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160158741
Domainoid	1	1.000	238	1.000	Domainoid score	I1286
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000203
OrthoInspector	1	1.000	-	-		otm14704
orthoMCL	1	0.900	-	-		OOG6_103647
Panther	1	1.100	-	-	LDO	PTHR23255
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5155
SonicParanoid	1	1.000	-	-		X151
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.870