Protein Alignment babo and Acvr2b

DIOPT Version :10

• Sequence 1: NP_476999.1
• Gene: babo / 35900
• FlyBaseID: FBgn0011300
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: XP_036010460.1
• Gene: Acvr2b / 11481
• MGIID: 87912
• Length: 557
• Species: Mus musculus
• Alignment Length: 438
• Identity: 145/438 - (33%)
• Similarity: 232/438 - (52%)
• Gaps: 58/438 - (13%)

  Fly   201 CCKDRDFCNRFLWPKTKDQRSDRVEE--GRQISVQ--DYVPHRLTSWEFVAIILGATLFICFTGT 261
            ||.:.:|||         :|...:.|  |.:::.:  ...|..||...:..:.:|....|..  .
Mouse   123 CCCEGNFCN---------ERFTHLPEPGGPEVTYEPPPTAPTLLTVLAYSLLPIGGLSLIVL--L 176

  Fly   262 STWYYCQRRKRMASGRTFAKEDSAYDPILNGNTTIHDIIEM-----TTSGSGSAGLPLLVQRS-- 319
            :.|.|..|:...                  |:..||::.:.     ...|...:..||..|..
Mouse   177 AFWMYRHRKPPY------------------GHVDIHEVRQCQRWAGRRDGCADSFKPLPFQDPGP 223

  Fly   320 -------IARQVQLCHVIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHEN 377
                   ..:.:||..:..:||||.||:.:...:.||||||..:::.||..|.||:.|..::|||
Mouse   224 PPPSPLVGLKPLQLLEIKARGRFGCVWKAQLMNDFVAVKIFPLQDKQSWQSEREIFSTPGMKHEN 288

  Fly   378 ILGFIAADNKDNGTWTQLWLVTDYHENGSLFDYLTTHPVDTNTMLNMSLSIATGLAHLHMDIVGT 442
            :|.||||:.:.:....:|||:|.:|:.|||.|||..:.:..|.:.:::.:::.||::||.|:...
Mouse   289 LLQFIAAEKRGSNLEVELWLITAFHDKGSLTDYLKGNIITWNELCHVAETMSRGLSYLHEDVPWC 353

  Fly   443 RG---KPAIAHRDLKSKNILVKSNLSCAIGDLGLAVRHVEKNDSVDIPSTH-RVGTKRYMAPEVL 503
            ||   ||:|||||.||||:|:||:|:..:.|.|||||........|   || :|||:||||||||
Mouse   354 RGEGHKPSIAHRDFKSKNVLLKSDLTAVLADFGLAVRFEPGKPPGD---THGQVGTRRYMAPEVL 415

  Fly   504 DESMNDQHFDSYKRADVYAFGLILWEIARRCNM--GMIYDEYQLPYYDVVQPDPSIEEMKKVVCI 566
            :.::|.|. |::.|.|:||.||:|||:..||..  |.: |||.||:.:.:...||:||:::||..
Mouse   416 EGAINFQR-DAFLRIDMYAMGLVLWELVSRCKAADGPV-DEYMLPFEEEIGQHPSLEELQEVVVH 478

  Fly   567 EKCRPNIPNRWHASDVLHNMAKVMKECWYPNPVARLTALRIKKTLASI 614
            :|.||.|.:.|.....|..:...::|||..:..|||:|..:::.::.|
Mouse   479 KKMRPTIKDHWLKHPGLAQLCVTIEECWDHDAEARLSAGCVEERVSLI 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
babo	NP_476999.1	TFP_LU_ECD_Babo	127..210	CDD:467127	4/8 (50%)
		GS	294..324	CDD:197743	6/43 (14%)
		STKc_TGFbR1_ACVR1b_ACVR1c	328..615	CDD:271045	120/293 (41%)
Acvr2b	XP_036010460.1	TFP_LU_ECD_ACVR2B	47..137	CDD:467152	6/22 (27%)
		STKc_ACVR2b	239..529	CDD:271042	120/293 (41%)