Protein Alignment babo and acvr1c

DIOPT Version :10

• Sequence 1: NP_476999.1
• Gene: babo / 35900
• FlyBaseID: FBgn0011300
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: XP_002933316.2
• Gene: acvr1c / 100487548
• XenbaseID: XB-GENE-487108
• Length: 537
• Species: Xenopus tropicalis
• Alignment Length: 505
• Identity: 260/505 - (51%)
• Similarity: 338/505 - (66%)
• Gaps: 48/505 - (9%)

  Fly   127 IKCHCDTCKESNNICETDGFCFTSVEKNSDGSIIFSYRCL----HKSQIFPPGRSIWCNDGLHGG 187
            :||.|..|:.:|..|:|:|.|:|||........:.. .|:    .|:|:|       |:
 Frog    70 LKCVCLLCENTNYTCQTEGACWTSVMLTHGKEEVLK-SCISLPEFKAQVF-------CH------ 120

  Fly   188 PTARPVGRNGAHACCKDRDFCNRFLWPKTKDQRSDRVEEGRQISVQDYVPHRLTSWEFVAIILGA 252
             ::..:.|.   .||.. ||||..      ..|...|..|  :|...:|       |...|:
 Frog   121 -SSNNITRT---ECCLS-DFCNNI------TLRLPAVTPG--VSHMGHV-------ELTVIV--- 162

  Fly   253 TLFICFTGT---STWYYCQRR--KRMASGRTFAKEDSAYDPILNGNTTIHDII-EMTTSGSGSAG 311
            |:.||....   .|.|.||.|  .:..:.|...:|.....|:.....::.|:| :|||||||| |
 Frog   163 TVSICLLSVVIMVTAYVCQERYCAKNKARRQCVEEPLTECPLDIAGKSLKDLIYDMTTSGSGS-G 226

  Fly   312 LPLLVQRSIARQVQLCHVIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHE 376
            |||||||:|||.|.:..::|||||||||||:|.||:|||||||||:|.|||||||||||||||||
 Frog   227 LPLLVQRTIARTVVIQELVGKGRFGEVWRGKWCGEDVAVKIFSSRDERSWFREAEIYQTVMLRHE 291

  Fly   377 NILGFIAADNKDNGTWTQLWLVTDYHENGSLFDYLTTHPVDTNTMLNMSLSIATGLAHLHMDIVG 441
            |||||||||||||||||||||::::||.|||||||..:.|....|:.::||:.:|||||||:|||
 Frog   292 NILGFIAADNKDNGTWTQLWLISEFHEQGSLFDYLNCNTVTIGGMMKLALSVVSGLAHLHMEIVG 356

  Fly   442 TRGKPAIAHRDLKSKNILVKSNLSCAIGDLGLAVRHVEKNDSVDIPSTHRVGTKRYMAPEVLDES 506
            |:||||||||||||||||||.|.:|.|.||||||:|....:::|||...|||||||||||:||:|
 Frog   357 TQGKPAIAHRDLKSKNILVKKNETCCIADLGLAVKHDSITNTIDIPQNPRVGTKRYMAPELLDDS 421

  Fly   507 MNDQHFDSYKRADVYAFGLILWEIARRCNMGMIYDEYQLPYYDVVQPDPSIEEMKKVVCIEKCRP 571
            :|..||||:|.:|:|:.||:.|||||||::|.:.|||||||||:|..|||:|:::||||.:|.||
 Frog   422 INTYHFDSFKCSDIYSLGLVYWEIARRCSVGGVVDEYQLPYYDMVPSDPSLEDVRKVVCEQKLRP 486

  Fly   572 NIPNRWHASDVLHNMAKVMKECWYPNPVARLTALRIKKTLASISVEDKVK 621
            :|||:|.:.:.|..|.::|:||||.|..|||||||||||::.:.||:..|
 Frog   487 SIPNQWQSFEALRIMGRIMRECWYANGKARLTALRIKKTISQLCVEEDYK 536

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
babo	NP_476999.1	TFP_LU_ECD_Babo	127..210	CDD:467127	23/86 (27%)
		GS	294..324	CDD:197743	21/30 (70%)
		STKc_TGFbR1_ACVR1b_ACVR1c	328..615	CDD:271045	193/286 (67%)
acvr1c	XP_002933316.2	TFP_LU_ECD_ALK7	68..143	CDD:467070	24/97 (25%)
		TGF_beta_GS	210..237	CDD:462503	19/27 (70%)
		STKc_TGFbR1_ACVR1b_ACVR1c	243..530	CDD:271045	193/286 (67%)