Protein Alignment CG8230 and DYM

DIOPT Version :9

• Sequence 1: NP_610431.1
• Gene: CG8230 / 35897
• FlyBaseID: FBgn0027607
• Length: 699
• Species: Drosophila melanogaster
• Sequence 2: XP_011524338.1
• Gene: DYM / 54808
• HGNCID: 21317
• Length: 745
• Species: Homo sapiens
• Alignment Length: 667
• Identity: 277/667 - (41%)
• Similarity: 407/667 - (61%)
• Gaps: 64/667 - (9%)

  Fly     1 MGINVSRTADLGSNQWLQRFVGRQHIAHDDEAFWNGLLNYNIVLPENSQDQLNLDSRLEALCQSF 65
            ||.|.||..||..|::|::..|.:.|:.:| .|||.||:::...|.:|.:...|:....::|:|.
Human     1 MGSNSSRIGDLPKNEYLKKLSGTESISEND-PFWNQLLSFSFPAPTSSSELKLLEEATISVCRSL 64

  Fly    66 IGNNLKTGNFGSLVTVFLEKTSELLSLSDQESNMHVWQTFNALFIIRSLVKYINETGSEFQLLQH 130
            :.||.:|||.|:|:.|||.:|.||...::.::::.:|||.||||||..|:|......||.:|..|
Human    65 VENNPRTGNLGALIKVFLSRTKELKLSAECQNHIFIWQTHNALFIICCLLKVFICQMSEEELQLH 129

  Fly   131 FEAMPNAELLQAALEQQQQTPAESATIAMEATEQSAAAAVPVIVDGSKFETFIDALVNLIVVIPV 195
            |             ..::::|...::.:.:..|:                 .:..|:.||..||:
Human   130 F-------------TYEEKSPGNYSSDSEDLLEE-----------------LLCCLMQLITDIPL 164

  Fly   196 KEFTYHLHLEAVNMLITLLSVHLFAQQPTDKSIVFRTVFK--C-QHANVLMSALLHFVARIVEVP 257
            .:.||.:.:||::.::..||..||.::...:||..:.:.:  | .:.:.|:..||:...|..:.|
Human   165 LDITYEISVEAISTMVVFLSCQLFHKEVLRQSISHKYLMRGPCLPYTSKLVKTLLYNFIRQEKPP 229

  Fly   258 ----HTMFGSSSAGSFVF----GIAESLLSIFTFRKQPDILKAGQAAGGGELSQRFRTHYPLANQ 314
                |.....|..|..::    |:|..|.::||...     ...:||...|||.      |||||
Human   230 PPGAHVFPQQSDGGGLLYGLASGVATGLWTVFTLGG-----VGSKAAASPELSS------PLANQ 283

  Fly   315 SLLLILILTNHCTAQD--NAYRTSLFSCADSKDS---PKQGAVSFQIDFSAVYETLCTIVTIDQA 374
            ||||:|:|.|...|.|  |.||.::.|..:::||   |.....:|||:|:::|..||...|.|||
Human   284 SLLLLLVLANLTDASDAPNPYRQAIMSFKNTQDSSPFPSSIPHAFQINFNSLYTALCEQQTSDQA 348

  Fly   375 TLLLYLLLHRNERFYRFVMQQQDLEQLVIPILQTLYNAPDSNSHHIYMSLIVLLILSEDEGFNKN 439
            |||||.|||:|.....:::.:.|:|.||:|||:.||:..:.||||:||:||:||||:||:|||::
Human   349 TLLLYTLLHQNSNIRTYMLARTDMENLVLPILEILYHVEERNSHHVYMALIILLILTEDDGFNRS 413

  Fly   440 VHTIMLKNITWYTERTISEISLGGILILIVIRTIQYNMLKMRDKYLHTNCLAALANMSGHFRALH 504
            :|.::|||||||:||.::|||||.:|||:|||||||||.:.|||||||||||||||||..||:||
Human   414 IHEVILKNITWYSERVLTEISLGSLLILVVIRTIQYNMTRTRDKYLHTNCLAALANMSAQFRSLH 478

  Fly   505 PYVAQRLVSLFETLARKHTRLDAQLKEPADSAVFVNVSTTPEDMLQDLSVLEEVLRMVLEILNSC 569
            .|.|||::|||..|::||.::..|..:....::..|....| |..|||:|:|||:||:|||:|||
Human   479 QYAAQRIISLFSLLSKKHNKVLEQATQSLRGSLSSNDVPLP-DYAQDLNVIEEVIRMMLEIINSC 542

  Fly   570 LTNQLVYCPNLVYTLLYKRSVFEGFRSHHAFQDVIQNIDMVVGFFSSRLQRVQEQRG-ELGVNEV 633
            |||.|.:.|||||.|||||.:||.||:|.:|||::||||:|:.||||||.    |.| ||.|..|
Human   543 LTNSLHHNPNLVYALLYKRDLFEQFRTHPSFQDIMQNIDLVISFFSSRLL----QAGAELSVERV 603

  Fly   634 LEVISKGASQWSSDRLR 650
            ||:|.:|......|||:
Human   604 LEIIKQGVVALPKDRLK 620

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8230	NP_610431.1	Dymeclin	1..676	CDD:286785	277/667 (42%)
DYM	XP_011524338.1	Dymeclin	1..618	CDD:286785	274/663 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153099
Domainoid	1	1.000	524	1.000	Domainoid score	I297
eggNOG	1	0.900	-	-		E1_KOG2225
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H69237
Inparanoid	1	1.050	526	1.000	Inparanoid score	I1239
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48855
OrthoDB	1	1.010	-	-		D152977at33208
OrthoFinder	1	1.000	-	-		FOG0005697
OrthoInspector	1	1.000	-	-		oto88580
orthoMCL	1	0.900	-	-		OOG6_104456
Panther	1	1.100	-	-	LDO	PTHR12895
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3721
SonicParanoid	1	1.000	-	-		X4094
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.800