Protein Alignment CG8230 and C47D12.2

DIOPT Version :9

• Sequence 1: NP_610431.1
• Gene: CG8230 / 35897
• FlyBaseID: FBgn0027607
• Length: 699
• Species: Drosophila melanogaster
• Sequence 2: NP_496492.1
• Gene: C47D12.2 / 174789
• WormBaseID: WBGene00008136
• Length: 689
• Species: Caenorhabditis elegans
• Alignment Length: 719
• Identity: 240/719 - (33%)
• Similarity: 397/719 - (55%)
• Gaps: 66/719 - (9%)

  Fly     1 MGINVSRTADLGSNQWLQRFVGRQHIAHDDEAFWNGLLNYNIVLPENSQD-QLNLDSRLEALCQS 64
            ||..:::...|..|.:|::..|.:.: .|.:.|||.||::::...::.:| ::.|:|.|:...|.
 Worm     1 MGSVITKETVLQENIYLKKLSGLEPV-DDYDPFWNKLLSFSLKFDDDDEDTRIALESALDDHLQC 64

  Fly    65 FIGNNLKTGNFGSLVTVFLEKTSELLSLSDQESNMHVWQTFNALFIIRSLVKYINETGSEFQLLQ 129
            .:.|...||||.:.:.:||.:.:||.:....|:.:::|||.|||.|:|.:.:::.
 Worm    65 LMYNTQTTGNFAAFIRLFLRRATELKTSEQCENKIYLWQTSNALLILRYIARFLT---------- 119

  Fly   130 HFEAMPNAELLQAALEQQQQTPAESATIAMEATEQ-------------SAAAAVPVIVDGSKFET 181
              :.|...|.::...:..:.|..||::.:..:.|:             .|...:|::...:. |.
 Worm   120 --QRMTEKEFVRIFAKSHESTETESSSTSSSSDEEDDDEQKSENENNNGATKYIPIVFQNTA-EE 181

  Fly   182 FIDALVNLIVVIPVKEFTYHLHLEAVNMLITLLSVHLFAQQPTDKSIVFRTVF--KC-QHA---- 239
            |...||::::.|.|.|.|..:|:|||..|:||||..|:.:...:.|||||...  .| :||
 Worm   182 FTYELVSILINISVNETTLAIHVEAVRCLLTLLSSQLYNESIVNTSIVFRFFIDGSCAKHAASLT 246

  Fly   240 -NVLMSALLHFVARIVEVPHTMFGSSSAGSFVFGIAESLLSIFTFRKQPDILKAGQAAGGGELSQ 303
             .:|::.|:|      ...:.|.......|.|||:|.|:.|:           ...|.|.....:
 Worm   247 KTLLLNYLIH------NSEYHMTVQKPQESIVFGLASSMWSM-----------VQMATGIDSAEE 294

  Fly   304 RFRTHYPLANQSLLLILILTNHCTA-QDNAYR--TSLFSCADSKDSPKQGAVSFQIDFSAVYETL 365
            ..:....|.|.|:||:|.|:.|... ..|.::  .:||..|....:.....|||:||::.:||.|
 Worm   295 EKKPPLTLGNLSILLLLNLSCHQPLNSSNPFKETLALFQNAQEVSTLPTQIVSFKIDYNGLYERL 359

  Fly   366 CTIVTIDQATLLLYLLLHRNERFYRFVMQQQDLEQLVIPILQTLYN--APDSNSHHIYMSLIVLL 428
            |.....:...||||:||..|..|..:|:.:.:||.||:|:|:.|::  |..:||||:|::|||.|
 Worm   360 CATAGQEPPMLLLYMLLQANSGFRNYVLSRINLENLVVPVLRILHDGVATSNNSHHVYLALIVAL 424

  Fly   429 ILSEDEGFNKNVHTIMLKNITWY-TERTISEISLGGILILIVIRTIQYNMLKMRDKYLHTNCLAA 492
            |||||:.|.|.:|..|:|::.|. ::.::.||||||:..|:::|.||.|.||.||:|||||||||
 Worm   425 ILSEDDIFCKIIHETMIKDLGWLDSDFSVREISLGGLTTLVLVRAIQKNALKTRDRYLHTNCLAA 489

  Fly   493 LANMSGHFRALHPYVAQRLVSLFETLARKHTRLDAQLKEPADSAVFVNVSTTPEDMLQDLSVLEE 557
            |||||..|:.|.|.|.|||:||.:.|.::|.::...::..:.:.|   ....|.:...|::.|||
 Worm   490 LANMSAFFKNLAPIVCQRLISLLDLLTKRHAKMVDHMRVSSQNDV---ADGQPINFHDDITALEE 551

  Fly   558 VLRMVLEILNSCLTNQLVYCPNLVYTLLYKRSVFEGFRSHHAFQDVIQNIDMVVGFFSSRLQRVQ 622
            .:|.:|||:||.|...|.:..:|:|.|||.|::|:.:..|..|||::.||..|:..|||::..|.
 Worm   552 GIRTLLEIINSALCGGLRHNSHLIYNLLYHRALFDAYVQHPMFQDLLVNIAAVISHFSSKVIHVP 616

  Fly   623 EQRGELGVNEVLEVISKGASQWSSDRLRKFPDLKFKYVEEDAPEEFFIPYVWTLVCKYGCVHFSS 687
            ...|    :.:|::|.|.|:.|.:|||.|||:|||:|||::...:||:||||.|..::..::|.:
 Worm   617 AGDG----STMLQIIEKEANIWPTDRLAKFPELKFRYVEDEYTVDFFVPYVWRLSVQHSGIYFET 677

  Fly   688 ESIK 691
            ..||
 Worm   678 SRIK 681

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8230	NP_610431.1	Dymeclin	1..676	CDD:286785	236/702 (34%)
C47D12.2	NP_496492.1	Dymeclin	1..666	CDD:286785	236/702 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160162748
Domainoid	1	1.000	381	1.000	Domainoid score	I440
eggNOG	1	0.900	-	-		E1_KOG2225
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H69237
Inparanoid	1	1.050	387	1.000	Inparanoid score	I1155
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48855
OrthoDB	1	1.010	-	-		D152977at33208
OrthoFinder	1	1.000	-	-		FOG0005697
OrthoInspector	1	1.000	-	-		oto19872
orthoMCL	1	0.900	-	-		OOG6_104456
Panther	1	1.100	-	-	LDO	PTHR12895
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3721
SonicParanoid	1	1.000	-	-		X4094
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	16	15.800