DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG13748 and Aplp2

DIOPT Version :9

Sequence 1:NP_610430.1 Gene:CG13748 / 35896 FlyBaseID:FBgn0033355 Length:113 Species:Drosophila melanogaster
Sequence 2:NP_037038.1 Gene:Aplp2 / 64312 RGDID:2128 Length:765 Species:Rattus norvegicus


Alignment Length:99 Identity:34/99 - (34%)
Similarity:48/99 - (48%) Gaps:16/99 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly    30 DLYDDVSDFFDAISLDDVANTGRNTHP---------------EQFCLMPARKGVCRALIPRWRYD 79
            ::.:|...::|:...||. |....|.|               :..|...|..|.|||::|||.:|
  Rat   268 EVVEDRDYYYDSFKGDDY-NEENPTEPSSDGTISDKEIAHDVKAVCSQEAMTGPCRAVMPRWYFD 331

  Fly    80 PEQKKCVEFKFGGCDGNENNFASYKDCMSTCEGM 113
            ..:.|||.|.:|||.||.|||.|...||:.|:.|
  Rat   332 LSKGKCVRFIYGGCGGNRNNFESEDYCMAVCKTM 365

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG13748NP_610430.1 Kunitz_BPTI 59..110 CDD:278443 25/50 (50%)
Aplp2NP_037038.1 A4_EXTRA 42..204 CDD:128326
GFLD subdomain. /evidence=ECO:0000255|PROSITE-ProRule:PRU01217 46..139
APP_N 49..147 CDD:280358
CuBD subdomain. /evidence=ECO:0000255|PROSITE-ProRule:PRU01217 147..205
APP_Cu_bd 149..204 CDD:289676
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 211..301 7/33 (21%)
Kunitz_BPTI 311..363 CDD:278443 25/51 (49%)
APP_E2 367..549 CDD:289677
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 597..616
APP_amyloid 711..761 CDD:287486
Interaction with DAB2. /evidence=ECO:0000250 751..765
NPXY motif 752..757
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4295
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
32.810

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