Protein Alignment PAN2 and REX3

DIOPT Version :10

• Sequence 1: NP_610427.2
• Gene: PAN2 / 35893
• FlyBaseID: FBgn0033352
• Length: 1241
• Species: Drosophila melanogaster
• Sequence 2: NP_013208.1
• Gene: REX3 / 850797
• SGDID: S000004097
• Length: 404
• Species: Saccharomyces cerevisiae
• Alignment Length: 301
• Identity: 66/301 - (21%)
• Similarity: 112/301 - (37%)
• Gaps: 93/301 - (30%)

  Fly   916 YHTMKLAESADDPQSQWYIFNDFSISPVSPQESVWFTLDWKVPCILFYRHV-----EDDSESAST 975
            ||.:|...:.|....|:....:.:       :||.|.   ::.|..|:.||     .|:....|.
Yeast   176 YHPLKRIYNRDTKNHQYPCCGETT-------DSVSFL---RLGCKTFFHHVFRGESYDELCKISK 230

  Fly   976 TSST-VTESEETIPSESSSGSPTNLSNPFLE-EIVSPMLGNLSADATLQPLQSDEMPQSGDLVAM 1038
            .||| ..:..|.:.|.....:.|:|....:. .||....|....|..:||:        ||:|.:
Yeast   231 FSSTDDIDGVENVLSLDCEMAFTSLGYEMIRLTIVDFFTGKTLFDHVIQPI--------GDIVDL 287

  Fly  1039 DAEFVTLNPEENEIRPDGKTATIKPCHMSVARISCIRGQGPAEGVPFMDDYISTQEKVVDYLTQF 1103
            :::|..::                    .:.|.:|                 .|.::.:|..
Yeast   288 NSDFSGVH--------------------EIDRTNC-----------------PTYKEALDVF--- 312

  Fly  1104 SGIKPGDLDANFSKKRLTALKYSYQKLKYLVDVGVIFVGHGLKNDFRVINIYVPSEQIIDTVHLF 1168
                   |..|                  |::...|.:||||:||..|:.::  ..::|||..|:
Yeast   313 -------LSEN------------------LINKNSILIGHGLENDLNVMRLF--HNKVIDTAILY 350

  Fly  1169 HMPHHRMVSLRFLAWHFLGTKIQSETHDSIEDARTTLQLYK 1209
            .....: |||:.||:..|..|||:..|||.:||..|:.:.|
Yeast   351 SRTKFK-VSLKNLAFEVLSRKIQNGEHDSSQDAIATMDVVK 390

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PAN2	NP_610427.2	WD40	63..>270	CDD:475233
		WD40 repeat	148..183	CDD:293791
		WD40 repeat	187..221	CDD:293791
		WD40 repeat	227..273	CDD:293791
		WD40 repeat	278..314	CDD:293791
		UCH_1	505..940	CDD:463872	5/23 (22%)
		zf-CCCH_2	799..816	CDD:464217
		PAN2_exo	1036..1209	CDD:99846	36/172 (21%)
REX3	NP_013208.1	REX1_like	244..390	CDD:99848	47/221 (21%)