DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PAN2 and aen

DIOPT Version :9

Sequence 1:	NP_610427.2	Gene:	PAN2 / 35893	FlyBaseID:	FBgn0033352	Length:	1241	Species:	Drosophila melanogaster
Sequence 2:	NP_001072399.2	Gene:	aen / 779853	XenbaseID:	XB-GENE-949418	Length:	360	Species:	Xenopus tropicalis

Alignment Length:	233	Identity:	75/233 - (32%)
Similarity:	103/233 - (44%)	Gaps:	37/233 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   986 TIPSESSSGSPTNLSNPF-LEEIVSPMLGNLSADATLQPLQSDEMPQSGDLVAMDAEFVTLNPEE 1049
            |:|....|....|..:.| .::....:.|:.|:.....||   ...:.|..||:|.|.|...
Frog   108 TLPVAPGSSITGNKPSTFDYDDSGLSVAGSSSSSRASSPL---SWLKPGKCVAIDCEMVGTG--- 166

  Fly  1050 NEIRPDGKTATIKPCHMSVARISCIRGQGPAEGVPFMDDYISTQEKVVDYLTQFSGIKPGDLDAN 1114
                |.||.:       .:||.|.:..:|..    ..|.||..:..:.||.|::|||....|...
Frog   167 ----PGGKIS-------ELARCSIVNYRGDV----VYDKYIKPELPIADYRTRWSGITKHSLKNA 216

  Fly  1115 FSKKRLTALKYSYQKLKYLVDVGVIFVGHGLKNDFRVINIYVPSEQIIDT--VHLFH----MPHH 1173
            .|.|  ||.|   :.||.|.|..|  |||.|.||||.:..:.|..||.||  :.|..    :|..
Frog   217 ISFK--TAQK---EILKILKDKRV--VGHALHNDFRALKYFHPHSQIRDTSKISLLKKNAGLPEK 274

  Fly  1174 RMVSLRFLAWHFLGTKIQ--SETHDSIEDARTTLQLYK 1209
            ..|||:.||.:.||.:||  ...|.|:|||..:|:|||
Frog   275 AGVSLKTLALNLLGKRIQVGRNGHSSVEDALASLELYK 312

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PAN2	NP_610427.2	WD40	63..>270	CDD:330360
		WD40 repeat	148..183	CDD:293791
		WD40 repeat	187..221	CDD:293791
		WD40 repeat	227..273	CDD:293791
		WD40 repeat	278..314	CDD:293791
		UCH_1	505..940	CDD:315986
		zf-CCCH_2	799..816	CDD:317060
		PAN2_exo	1036..1209	CDD:99846	63/180 (35%)
aen	NP_001072399.2	DnaQ	150..>323	CDD:223916	66/188 (35%)
aen	NP_001072399.2	DnaQ_like_exo	156..312	CDD:299142	63/180 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910