Protein Alignment PAN2 and Aen

DIOPT Version :10

• Sequence 1: NP_610427.2
• Gene: PAN2 / 35893
• FlyBaseID: FBgn0033352
• Length: 1241
• Species: Drosophila melanogaster
• Sequence 2: NP_080807.3
• Gene: Aen / 68048
• MGIID: 1915298
• Length: 336
• Species: Mus musculus
• Alignment Length: 239
• Identity: 70/239 - (29%)
• Similarity: 102/239 - (42%)
• Gaps: 56/239 - (23%)

  Fly  1028 EMPQSGDL--VAMDAEFVTLNPEENEIRPDGKTATIKPCHMSVARISCIRGQGPAEGVPFMDDYI 1090
            |.|:.|.:  ||:|.|.|...|:       |:.:.:..|  ||...|         |....|.||
Mouse   100 EAPRPGPIKCVAIDCEMVGTGPQ-------GRVSELARC--SVVSYS---------GDVLYDKYI 146

  Fly  1091 STQEKVVDYLTQFSGIKPGDLDANF-----SKKRLTALKYSYQKLKYLVDVGVIFVGHGLKNDFR 1150
            ..:..:|||.|::|||....:....     .|:.|..||            |.:.|||.|.|||:
Mouse   147 RPEMPIVDYRTRWSGITRQHMHKAIPFQVAQKEILKLLK------------GKVVVGHALHNDFQ 199

  Fly  1151 VINIYVPSEQIIDTVH---LFHMPH---HRMVSLRFLAWHFLGTKIQ--SETHDSIEDARTTLQL 1207
            .:....|..|..||.:   |...|.   ...|||:.||.:.|..|||  .:.|.|:|||.|.::|
Mouse   200 ALKYVHPRSQTRDTTYVPNLLSQPSSLIRTRVSLKDLALNLLHKKIQVGHQGHSSVEDAMTAMEL 264

  Fly  1208 YKHYLKLQEEKKFANALKNLYE-RGKQLQWKV---------PED 1241
            |: .:::|.|::.|::.:...| ||......|         |||
Mouse   265 YQ-LVEVQWEQQVASSAQAPAEDRGPDSSTDVEQYMDDQYWPED 307

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PAN2	NP_610427.2	WD40	63..>270	CDD:475233
		WD40 repeat	148..183	CDD:293791
		WD40 repeat	187..221	CDD:293791
		WD40 repeat	227..273	CDD:293791
		WD40 repeat	278..314	CDD:293791
		UCH_1	505..940	CDD:463872
		zf-CCCH_2	799..816	CDD:464217
		PAN2_exo	1036..1209	CDD:99846	56/185 (30%)
Aen	NP_080807.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..37
		Nucleolar localization signal. /evidence=ECO:0000250	25..33
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	56..102		1/1 (100%)
		DnaQ_like_exo	110..266	CDD:447876	56/185 (30%)
		Nuclear localization signal. /evidence=ECO:0000250	164..187		4/34 (12%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	276..336		8/32 (25%)