Protein Alignment PAN2 and Rexo1

DIOPT Version :9

• Sequence 1: NP_610427.2
• Gene: PAN2 / 35893
• FlyBaseID: FBgn0033352
• Length: 1241
• Species: Drosophila melanogaster
• Sequence 2: XP_011241832.1
• Gene: Rexo1 / 66932
• MGIID: 1914182
• Length: 1228
• Species: Mus musculus
• Alignment Length: 541
• Identity: 113/541 - (20%)
• Similarity: 181/541 - (33%)
• Gaps: 178/541 - (32%)

  Fly   731 EKSIQAFCERCKKFSPTNQSVKVTSLPQILSINCGLNNEKDITFLKRQLNRCSEKTTVDAAASLS 795
            ::.:..|.|.|.||..:||.          :|...||.|| :.:.:      |....:....:::
Mouse   811 QRYLNLFIEECLKFCSSNQE----------AIEKALNEEK-VAYDR------SPSKNIYLNVAVN 858

  Fly   796 TSKPCRYGANCSRSDCHFMHPDRKSPSHTSQPNAVNNSPNGRQKSWFPLTFTMGINDQ------- 853
            |.|..|                      ...||.|.|      .|.| |.|.:..:.:
Mouse   859 TLKKLR----------------------GLVPNTVPN------LSTF-LYFLLEASGRRVVSHEV 894

  Fly   854 ---GEVQVQTQSDASSGKSEQEEE----TEKPP--TKGLDNNRMYALHAVVCQVDDGTQKNLVSL 909
               |::..:|....|...|.:.||    |...|  |......|.|.|          ||:.|
Mouse   895 VLGGKLAAKTSFSLSRPSSPRVEELKALTHSAPAGTALYSRLREYLL----------TQEQL--- 946

  Fly   910 INVQRPYHTMKLAESADDPQSQWYIFNDFSISPVSPQESVWFTLDWKVP----CILFYRHVEDDS 970
                               :...|.|.    .|..|..::.||.:.|.|    |.:..|   ..:
Mouse   947 -------------------KENGYPFP----HPERPGGAIIFTAEEKKPKDPSCRICCR---CGT 985

  Fly   971 ESASTTSSTVTESEETI-------PSESSSGSPTNLSNPFLEEIVSPMLGNLSADATLQPLQ--- 1025
            |...::|.....|||..       .:..:.|..|...      ..|..:|::......|.:|
Mouse   986 EYLVSSSGRCVRSEECYYHWGRLRRNRVAGGWETQYM------CCSAAVGSVGCQVAKQHVQDGR 1044

  Fly  1026 -----------SDEMPQS--GDLVAMDAE--FVTLNPEENEIRPDGKTATIKPCHMSVARISCIR 1075
                       ..|:|:.  ..:.|:|.|  :.|...|...:       |:....|.|.
Mouse  1045 KENLEGFVRTFQKELPEDAHAGVFALDCEMSYTTYGLELTRV-------TVVDTDMQVV------ 1096

  Fly  1076 GQGPAEGVPFMDDYISTQEKVVDYLTQFSGIKPGDL-DANFSKKRLTALKYSYQKLKYLVDVGVI 1139
                      .|.::....:||||.|:|||:...|| |.:.:.:.:.|:..|      :.....|
Mouse  1097 ----------YDTFVKPDNEVVDYNTRFSGVTEADLVDTSITLRDVQAVLLS------MFSADTI 1145

  Fly  1140 FVGHGLKNDFRVINIYVPSEQIIDTVHLF-H---MPHHRMVSLRFLAWHFLGTKIQS--ETHDSI 1198
            .:||.|::|  ::.:.|....::||..|| |   :|:.|  |||.|...:|...||.  :.|.|.
Mouse  1146 LIGHSLESD--LLALKVIHGTVVDTSVLFPHRLGLPYKR--SLRNLMADYLRQIIQDNVDGHSSS 1206

  Fly  1199 EDARTTLQLYKHYLKLQEEKK 1219
            |||...:.|.  ..|::|:.|
Mouse  1207 EDASACMHLV--IWKIREDAK 1225

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PAN2	NP_610427.2	WD40	63..>270	CDD:330360
		WD40 repeat	148..183	CDD:293791
		WD40 repeat	187..221	CDD:293791
		WD40 repeat	227..273	CDD:293791
		WD40 repeat	278..314	CDD:293791
		UCH_1	505..940	CDD:315986	41/224 (18%)
		zf-CCCH_2	799..816	CDD:317060	1/16 (6%)
		PAN2_exo	1036..1209	CDD:99846	48/181 (27%)
Rexo1	XP_011241832.1	PHA03307	150..>461	CDD:223039
		EloA-BP1	794..969	CDD:374185	45/239 (19%)
		REX1_like	1068..1216	CDD:99848	47/180 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0847
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810