DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PAN2 and Rexo5

DIOPT Version :9

Sequence 1:	NP_610427.2	Gene:	PAN2 / 35893	FlyBaseID:	FBgn0033352	Length:	1241	Species:	Drosophila melanogaster
Sequence 2:	XP_038934563.1	Gene:	Rexo5 / 309036	RGDID:	1305412	Length:	846	Species:	Rattus norvegicus

Alignment Length:	293	Identity:	83/293 - (28%)
Similarity:	114/293 - (38%)	Gaps:	84/293 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   990 ESSSGSPTNLSNPFLEEIVSPMLGNLSADATLQ------------------------PLQ----- 1025
            :|:.|.|..:..|.:...:...: :|..|..:|                        |||
  Rat   141 KSARGCPRTVEGPLISATLKSSI-DLQNDPIIQKYGYKNVSLTRCLLTKEEMKTFHFPLQGSPNC 204

  Fly  1026 --------SDEMPQSGDLVAMDAEFVTLNPEENEIRPDGKTATIKPCHMSVARISCIRGQGPAE- 1081
                    |..:..|..|..:|.| |.|.....|:                .|||.:     ||
  Rat   205 ENFILLKYSGFITDSSPLFGLDCE-VCLTSMGKEL----------------TRISLV-----AEG 247

  Fly  1082 GVPFMDDYISTQEKVVDYLTQFSGIKPGDLDANFSKKRL----TALKYSYQKLKYLVDVGVIFVG 1142
            |...||:.:....|::||||.||||         :|:.|    |.||...:.|:.|:....:.||
  Rat   248 GYCLMDELVKPDFKILDYLTSFSGI---------TKEILNPVTTKLKDVQKLLRELLPPDAVLVG 303

  Fly  1143 HGLKNDFRVINIYVPSEQIIDTVHLFHMPHHRMVSLRFLAWHFLGTKIQSET---HDSIEDARTT 1204
            |.|..|.||:.|..|  .:|||..|:.....|...|.|||...||..||...   ||.||||||.
  Rat   304 HCLDLDLRVLKIIHP--YVIDTSLLYIGKQGRRFKLTFLAKVILGKDIQCPNKLGHDGIEDARTA 366

  Fly  1205 LQLYKHYLKLQEEKKFA----NALKNLYERGKQ 1233
            |:|.:::|| ...||.|    .||....|:|.:
  Rat   367 LELVQYFLK-YGPKKIAEFNLEALAANQEQGNK 398

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PAN2	NP_610427.2	WD40	63..>270	CDD:330360
		WD40 repeat	148..183	CDD:293791
		WD40 repeat	187..221	CDD:293791
		WD40 repeat	227..273	CDD:293791
		WD40 repeat	278..314	CDD:293791
		UCH_1	505..940	CDD:315986
		zf-CCCH_2	799..816	CDD:317060
		PAN2_exo	1036..1209	CDD:99846	61/180 (34%)
Rexo5	XP_038934563.1	REX1_like	223..371	CDD:99848	61/180 (34%)
		RRM_SF	508..578	CDD:418427
		RRM_SF	604..674	CDD:418427
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0847
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810