Protein Alignment PAN2 and isg20

DIOPT Version :10

• Sequence 1: NP_610427.2
• Gene: PAN2 / 35893
• FlyBaseID: FBgn0033352
• Length: 1241
• Species: Drosophila melanogaster
• Sequence 2: XP_003201484.2
• Gene: isg20 / 100534720
• ZFINID: ZDB-GENE-100422-17
• Length: 338
• Species: Danio rerio
• Alignment Length: 278
• Identity: 76/278 - (27%)
• Similarity: 110/278 - (39%)
• Gaps: 72/278 - (25%)

  Fly   953 LDWKVPCILFYRHVEDDSESASTTSSTVTE------------SEETIPSESSSGSPTNLSNPFLE 1005
            ||.|..||           ...:||..|:|            :..|:|.||     ..:.:.|..
Zfish    66 LDNKTECI-----------KNGSTSDFVSEESNNMQFKRPRLTHHTLPGES-----WEVDSGFSS 114

  Fly  1006 EIVSPMLGNLSADATLQP-LQSDEMPQSGDLVAMDAEFVTLNPEENEIRPDGKTATIKPCHMSVA 1069
            |...|..|..|      | |:.|.    ..:||||.|.|...       |.|:.:       .||
Zfish   115 ESSPPTSGRSS------PCLRIDH----SRIVAMDCEMVGTG-------PGGRRS-------EVA 155

  Fly  1070 RISCIRGQGPAEGVPFMDDYISTQEKVVDYLTQFSGIKPGDLDANFSKKRLTALKYSYQKLKYLV 1134
            |.|.:...|..    ..|.||..|:.|.||.|::|||:...|      ::....:::..::..::
Zfish   156 RCSIVDYYGNV----VYDSYILPQDPVTDYRTRWSGIRSHHL------RQAVPFEHAQNEILKIL 210

  Fly  1135 DVGVIFVGHGLKNDFRVINIYVPSEQIIDTV------HLFHMPHHRMVSLRFLAWHFLGTKIQ-- 1191
            . |.|.|||.|.:|..|:.|.|....|.||.      .|:.:..:..:||:.||...|...||
Zfish   211 K-GKIIVGHALYHDLNVLYISVQPHMIRDTCSCVLLRQLYDVNQNCNISLKKLAQKLLNRTIQVD 274

  Fly  1192 SETHDSIEDARTTLQLYK 1209
            .:.|.|:|||.:.|.|||
Zfish   275 RQGHCSVEDALSALDLYK 292

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PAN2	NP_610427.2	WD40	63..>270	CDD:475233
		WD40 repeat	148..183	CDD:293791
		WD40 repeat	187..221	CDD:293791
		WD40 repeat	227..273	CDD:293791
		WD40 repeat	278..314	CDD:293791
		UCH_1	505..940	CDD:463872
		zf-CCCH_2	799..816	CDD:464217
		PAN2_exo	1036..1209	CDD:99846	53/180 (29%)
isg20	XP_003201484.2	ISG20	136..292	CDD:99852	53/180 (29%)