DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment AIMP1 and aimp1a

DIOPT Version :9

Sequence 1:	NP_610426.2	Gene:	AIMP1 / 35892	FlyBaseID:	FBgn0033351	Length:	323	Species:	Drosophila melanogaster
Sequence 2:	NP_001039316.1	Gene:	aimp1a / 562232	ZFINID:	ZDB-GENE-060825-144	Length:	315	Species:	Danio rerio

Alignment Length:	313	Identity:	144/313 - (46%)
Similarity:	203/313 - (64%)	Gaps:	17/313 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 KFARNKRTMADLQQIASNNERAEALINSIEAEISGIQQ----QLVERQKQELIKENAALAKEVEA 82
            |.:.:..::..|:|.|:   .||.:|..::.::..:::    |...:::::|:.|||.|.|::|.
Zfish     9 KMSGHTPSLMRLEQKAA---EAEQIIEYLKQQVQLLKEKAIVQATLKEEKKLMVENAKLKKDIEE 70

  Fly    83 ALAQLVQLELRNGKKQIPVPGARGFC----TSAAPVVMPAEAGPATAAPAAPAPKPAKEPKEKKS 143
            ...||:..|...|...:|.......|    |||.|   |..|.|:.|:...|:.|...|.|:.|:
Zfish    71 LKKQLLDKEKMRGVIDVPSTEFSVQCVSKPTSADP---PVSASPSAASTKTPSAKNNDEAKKMKA 132

  Fly   144 KEKKPAAEKPAAAP---EAPVDVGRLDLRVGKIVEVGRHPDADSLYLEKIDCGEAAPRTVVSGLV 205
            ::|....||.||||   :|.|||.|||||||:|:...:||||||||:|::|.|||||||||||||
Zfish   133 EKKGEKKEKKAAAPPQEDAKVDVSRLDLRVGRIISAEKHPDADSLYVEQVDVGEAAPRTVVSGLV 197

  Fly   206 KFVPLEEMQNRLVVVMCNLKPAKMRGVTSEAMVMCASTPEKVEVLSPPAGAVPGDLVHCEGYPRQ 270
            |.:||::||||:.|::|||||||||||.|:|||||||:|||||:|.||:||..||.:..:|:|.:
Zfish   198 KHIPLDQMQNRMAVLLCNLKPAKMRGVLSQAMVMCASSPEKVEILDPPSGAAAGDRITFQGFPGE 262

  Fly   271 PDAQLNPKKKIFESCAPDLKTNGELVACYKGAALHVPGKGNVVAQTLKNVNVK 323
            ||.:||||||::|...|||.|:.:.||.|||.|..|.|||...|||:....:|
Zfish   263 PDKELNPKKKVWEQVQPDLLTDDQCVATYKGVAFEVTGKGVCKAQTMSKSGIK 315

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AIMP1	NP_610426.2	tRNA_bind_EMAP-II_like	161..262	CDD:239198	73/100 (73%)
aimp1a	NP_001039316.1	ATP-synt_B	<5..81	CDD:304375	18/74 (24%)
aimp1a	NP_001039316.1	tRNA_bind_EMAP-II_like	153..255	CDD:239198	73/101 (72%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592432
Domainoid	1	1.000	148	1.000	Domainoid score	I4434
eggNOG	1	0.900	-	-		E1_COG0143
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H31260
Inparanoid	1	1.050	264	1.000	Inparanoid score	I3065
OMA	1	1.010	-	-		QHG56436
OrthoDB	1	1.010	-	-		D1434247at2759
OrthoFinder	1	1.000	-	-		FOG0000771
OrthoInspector	1	1.000	-	-		otm26397
orthoMCL	1	0.900	-	-		OOG6_100893
Panther	1	1.100	-	-	LDO	PTHR11586
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1946
SonicParanoid	1	1.000	-	-		X2386
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800