Protein Alignment CG8243 and Smap1

DIOPT Version :10

• Sequence 1: NP_610424.1
• Gene: CG8243 / 35890
• FlyBaseID: FBgn0033349
• Length: 517
• Species: Drosophila melanogaster
• Sequence 2: XP_003750716.3
• Gene: Smap1 / 684800
• RGDID: 1585595
• Length: 467
• Species: Rattus norvegicus
• Alignment Length: 543
• Identity: 180/543 - (33%)
• Similarity: 250/543 - (46%)
• Gaps: 125/543 - (23%)

  Fly     1 MSSSNAGQRTKLIQEKCQTLLTQMLRDEDNKYCVDCDAKGPRWASWNLGMFLCIRCAGIHRNLGV 65
            |::.:..::.:.:.|:.|.:|:::||:||||||.||:||||||||||:|:|:|||||||||||||
  Rat     1 MATRSCREKAQKLNEQHQLILSKLLREEDNKYCADCEAKGPRWASWNIGVFICIRCAGIHRNLGV 65

  Fly    66 HISRVKSVNLDTWTPEQVISLQQMGNSRARAVYEAQLPDGFRRPQTDTALENFIRAKYEHKKYLA 130
            |||||||||||.|||||:..:|.|||::||.:|||.||:.|||||||.|:|.|||.|||.|||..
  Rat    66 HISRVKSVNLDQWTPEQIQCMQDMGNTKARLLYEANLPENFRRPQTDQAVEFFIRDKYEKKKYYD 130

  Fly   131 REWV------------------PPSPPKVDWAKEIDEELERQKRKKKSTQAQATLGLAGVAGGSG 177
            :..:                  |..|..|| ..:|::|.|::|.:||..:             ..
  Rat   131 KNAIAITNISSSDAPLQPLVSSPSLPAAVD-KNKIEKEKEKKKEEKKREK-------------EP 181

  Fly   178 DKRLSGSSASALKNTPLPAPLPKPKPNQVGGCSPKTTQRVQLNSSGVSSAGESDLLGLSSPTK-P 241
            :|.....:...|:......|.||.      ..|||......:           |||||..|.: |
  Rat   182 EKPAKALTTEKLQKKEDQQPEPKK------STSPKNVAEPTV-----------DLLGLDGPAEAP 229

  Fly   242 IVATNA------SQDLQNESFTSFLSAE-SIAGQPDKPIGSNGDAANLMGSKPNSLAQEEQDFFN 299
            :...|.      |.||  :.|...:|.. ..|..|.    :.|.|:....:..:::...:.|.|.
  Rat   230 VTNGNTTAAPPLSDDL--DIFGPMISNPLPAAVMPQ----AQGTASIPAAAALSTITSGDLDLFT 288

  Fly   300 QGSLGAGGNEKDQSGKMSKDSILALYGSAPATHNPQMNFG----GFTGMAPGGYMHQQQQQQIPH 360
            :.:..:....|.|   :||||||:|||:......|.:..|    .||..||..:      |..|
  Rat   289 EQTTKSEEGAKKQ---LSKDSILSLYGTGAQQSTPGVFMGPTNIPFTSQAPTAF------QGFP- 343

  Fly   361 QFMTPPNSVSMYNSPVMAAPNAFSNAAISSATAMSMG--GSHGFTGAQFPSTGGSPYAAAGQAAA 423
                     || ..||.|||....| .:...|.|.:|  ..:||.|                .|.
  Rat   344 ---------SM-GVPVPAAPGLMGN-MMGQNTGMMVGMPMHNGFMG----------------NAQ 381

  Fly   424 TNLMQTNQSILSGMPLFGAVPQ-----------QQQQHQQQLQQQHHPQLGGLSMNLMQPLPSGL 477
            |.:|...|:::.  |..|.|.|           |.||.|..|.|.:...   .:||| ....|..
  Rat   382 TGVMPLPQNVVG--PQGGMVGQMGAPQSKFGLPQAQQPQWSLSQMNQQM---AAMNL-SSANSSA 440

  Fly   478 NIGQPPQGAGGF--AATGPTTSS 498
            ..||||....|:  :::|.|.|:
  Rat   441 GFGQPPSTTAGWSGSSSGQTLST 463

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8243	NP_610424.1	COG5347	20..300	CDD:227651	118/305 (39%)
		ArfGap_SMAP	21..123	CDD:350068	75/101 (74%)
Smap1	XP_003750716.3	ArfGap_SMAP	21..120	CDD:350068	73/98 (74%)