Protein Alignment CG8243 and arfgap2

DIOPT Version :9

• Sequence 1: NP_610424.1
• Gene: CG8243 / 35890
• FlyBaseID: FBgn0033349
• Length: 517
• Species: Drosophila melanogaster
• Sequence 2: XP_005159305.1
• Gene: arfgap2 / 641490
• ZFINID: ZDB-GENE-051120-177
• Length: 551
• Species: Danio rerio
• Alignment Length: 582
• Identity: 125/582 - (21%)
• Similarity: 217/582 - (37%)
• Gaps: 134/582 - (23%)

  Fly    19 TLLTQMLRDEDNKYCVDCDAKGPRWASWNLGMFLCIRCAGIHRNLGVHISRVKSVNLDT-WTPEQ 82
            |:..::.....||.|.||.||.|.|||.:.|:||||.|:||||:||||:|.::|..||: |...|
Zfish    12 TIFKRLRSIPTNKACFDCAAKNPSWASISYGVFLCIDCSGIHRSLGVHLSFIRSTELDSNWNWFQ 76

  Fly    83 VISLQQMGNSRARAVYEAQLPDGFRRPQTDTALENFIRAKYEHK------------------KYL 129
            :..:|..||:.|.         ||.|....|.  |...|||..:                  ||.
Zfish    77 LRCMQVGGNANAM---------GFFRQHGCTT--NDTNAKYNSRAAQMYREKIRQLANAALSKYG 130

  Fly   130 AREWV------PPSPPKVDWAKEIDEELERQKRKKKSTQAQATLGLA--GVAGGSGDKRLSGSSA 186
            ...|:      .|||.:.......||.          ||...:..:|  .:...:|.:.::...|
Zfish   131 TDLWIDSSSCAQPSPVEKRETDFFDEH----------TQPAISWDMASPSLTDQNGAENVNPQLA 185

  Fly   187 -SALKNTPLPAPLPKPKPNQVG-GCSPKTT--QRVQLNSSGVSSAGE--SDLLGLSSPTKPIVAT 245
             |..||:..|...|:..|:..| ..|||.|  ..::|.|....|..:  ..::|...|.......
Zfish   186 QSNPKNSETPNTQPEEGPSIEGLSTSPKATIEDSMRLTSEEPQSPKDVKPSIIGKKKPVAAKKGL 250

  Fly   246 NASQDLQNESFTSFLSAESIAGQPDKPIGSNGDAANLMGSKPNSLAQEEQDFFNQGSLGAGGNEK 310
            .|.:.         |.|:.::.:....:......|..|..:..:.|:::.|.....|:.....|.
Zfish   251 GAKKG---------LGAQKVSSKSFSEVEKQAQVAEKMREEQAAEAKKQADESIVASMRLAYKEL 306

  Fly   311 DQSGKMSKDSILALYG-SAPATHNPQMNFGGFTGMAPGGYMHQQQ--QQQIPHQFMTPPNS-VSM 371
            :...||.:..:..|.| .........|.||..:.:: ...|.:.|  :|:.|....:...| :.|
Zfish   307 EIDRKMEEKKMQNLEGKKKEQAERLGMGFGNRSAVS-HSVMAEMQVIEQETPVGVKSSSRSKLDM 370

  Fly   372 YNSPVMAA-PNAFSNAAISSATAMSMGGSHGFTGAQFPSTGGSPYAA---------AGQAAATNL 426
            :..|..|: |..:.:...:|..:.         |:::.:.|||.:::         ..:...:::
Zfish   371 FEEPGFASGPPKYKDNPFTSGDSF---------GSRWDNDGGSSFSSWALEKEEPKDSEVTISSI 426

  Fly   427 MQTNQSILSGMPLFGAVPQQQQQHQQQ-------------LQQQHHPQ------LGGLSMNL--- 469
            ....:.:.|......:||..:....:|             ..::.:|:      |.|:|.:.
Zfish   427 QPIGERLPSRRKPEVSVPVSESSEARQKFANAKAISSDMFFGRESNPEYEAKTRLEGMSGSTSIS 491

  Fly   470 ---------MQP---------LPSGLNIGQPPQG----AGGFAATGPTTSSVPSNLNQQFGN 509
                     ::|         ||||.:|.|..||    ||..|.   ..:.|.:.:..::|:
Zfish   492 SADLFGDGSVRPSGSTGFDSVLPSGPDIAQFKQGVKTVAGKMAV---LANGVMNTIQDRYGS 550

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8243	NP_610424.1	ArfGap	18..132	CDD:279720	46/131 (35%)
		COG5347	20..300	CDD:227651	79/312 (25%)
arfgap2	XP_005159305.1	PLN03114	1..498	CDD:178661	111/525 (21%)
		ArfGap	13..117	CDD:279720	43/114 (38%)
		TMF_DNA_bd	270..331	CDD:289127	10/60 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5347
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810