Protein Alignment CG8243 and appl1

DIOPT Version :9

• Sequence 1: NP_610424.1
• Gene: CG8243 / 35890
• FlyBaseID: FBgn0033349
• Length: 517
• Species: Drosophila melanogaster
• Sequence 2: XP_021335332.1
• Gene: appl1 / 571540
• ZFINID: ZDB-GENE-081016-1
• Length: 708
• Species: Danio rerio
• Alignment Length: 375
• Identity: 71/375 - (18%)
• Similarity: 118/375 - (31%)
• Gaps: 121/375 - (32%)

  Fly    65 VHISRVKSVNLDTWTPEQVISLQQMGNSRARAVYEAQLPDGFRRPQTDTALENFIRAKYEHKKYL 129
            |:.||.|.   ...|.....||..:...:..|:.|..|  |:.:.|.     :|.:...|:   |
Zfish   167 VYTSRKKQ---HETTMHYFASLNMLQYKKKIALLEPLL--GYMQAQI-----SFFKLGSEN---L 218

  Fly   130 AREWVPPSPPKVDWAKEIDEELERQKRKKKSTQAQATLGLAGVAGGSGDKRLSGSSASALKNTPL 194
            .::|       .|:...|...::..:|:..|                 |......:...||....
Zfish   219 TQQW-------EDFLTNIGTSVQNVRREMDS-----------------DAEAMEQTIQDLKEASD 259

  Fly   195 PAPLPKPKPNQVGGCSPKTTQRVQLNSSG----VSSAGESDLL-----GLSSPTKPIVATNASQD 250
            |..:|.|.||::......|.:...||:..    |||:.|....     .|.|.::..||.....|
Zfish   260 PLYMPDPDPNRIPVNRNLTRKAGYLNTRNKTGLVSSSWERQYFFTQGGNLMSQSRGAVAGGLVMD 324

  Fly   251 LQNES--------------FTSF-------LSAES-------------------IAGQPDKPIGS 275
            :.|.|              .|:|       |.|:|                   ::..|:: |.:
Zfish   325 IDNCSVMAVDCEDRRFCFQITAFDGKKAAVLQADSRKDCEEWIATINNISKRIYLSENPEE-IAA 388

  Fly   276 NGDAANLMGSKPNSLAQEEQDFF---NQGSLGAG--------GNEKDQSGKMSKDSILA------ 323
            ..:.:.|....|:...|:..:.|   .||.:.|.        |:|......:|.||::|
Zfish   389 RVNQSALEAVTPSPSFQQRHESFRPNTQGKVKASRSGSQCSVGSESPALSSLSLDSLVAPDTPIQ 453

  Fly   324 --LYGSAPATHNPQMN----------FGGFTGMAPGGYMHQQQQQQIPHQ 361
              :.......|..|..          ||     ..||...::.:..|.||
Zfish   454 FDIISPVSEEHTSQTKSSAQGRRTNPFG-----ESGGSQSEESEDSILHQ 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8243	NP_610424.1	ArfGap	18..132	CDD:279720	15/66 (23%)
		COG5347	20..300	CDD:227651	53/286 (19%)
appl1	XP_021335332.1	BAR_APPL1	20..234	CDD:153315	18/86 (21%)
		BAR-PH_APPL	252..376	CDD:270067	26/123 (21%)
		PTB_APPL	488..623	CDD:269980	3/11 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5347
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900