Protein Alignment CG8243 and asap2a

DIOPT Version :9

• Sequence 1: NP_610424.1
• Gene: CG8243 / 35890
• FlyBaseID: FBgn0033349
• Length: 517
• Species: Drosophila melanogaster
• Sequence 2: XP_021322892.1
• Gene: asap2a / 570669
• ZFINID: ZDB-GENE-041210-256
• Length: 1003
• Species: Danio rerio
• Alignment Length: 542
• Identity: 115/542 - (21%)
• Similarity: 189/542 - (34%)
• Gaps: 178/542 - (32%)

  Fly    12 LIQEKCQTLLTQMLRDEDNKYCVDCDAKGPRWASWNLGMFLCIRCAGIHRNLGVHISRVKSVNLD 76
            ::||..:.:|.::.|...|..|.||.|.||.|.|.|||:..||.|:||||.||||.||::|:.||
Zfish   427 IVQELTKAILGEVKRMAGNDVCCDCGAPGPTWLSTNLGILTCIECSGIHRELGVHYSRIQSLTLD 491

  Fly    77 TWTPEQVISLQQMGNSRARAVYEAQL--PDGFR-RPQTD-TALENFIRAKYEHKKYLAREWVPPS 137
            ..:..:::..:.:||:....:.||.|  .|..: .|.:| .|.::||.|||..|:: ||:..|.:
Zfish   492 VLSTSELLLAKNVGNAGFNEIMEACLTAEDVIKPNPASDMQARKDFIMAKYTEKRF-ARKKCPDA 555

  Fly   138 PPK---------------------------------------------------------VDWAK 145
            ..|                                                         :|:..
Zfish   556 LSKLHTLCDAVKARDIFSLIQVYAEGVDLMEPIPLANGHEQGETALHLAVRLVDRTSLHIIDFLT 620

  Fly   146 EIDEELERQKRK-----------------KKSTQAQATLGLAGVAGGSG---DKRLSGSSASALK 190
            :....|::|..|                 |...:.:|::.:|..||.:.   .:||.......|.
Zfish   621 QNSLNLDKQTAKGSTALHYCCLTDNSECLKLLLRGKASIDIANEAGETPLDIARRLKHLQCEELL 685

  Fly   191 NTPLPAPL-----------------------------PKPKPNQVGGCSPKTTQRVQLNSSGVSS 226
            |..|....                             |..:..:...|....:..:||:.:.:|.
Zfish   686 NQALAGKFNAHVHVEYEWRLQHEDLDESDEDLDEKSSPHRRDERPISCYTPGSNSLQLSPASLSR 750

  Fly   227 AGESDLLGLSSPTKPIVATNASQDLQNESFTSFLSAESIAGQPDKPIGSNGDA-----ANLMGSK 286
            .|. ||:.......|.:       :.||::.:.::..|       |:..:..|     .||:  :
Zfish   751 DGR-DLVKDKQRFVPNL-------VNNETYGTIINTSS-------PVSLSSSAPPLPPRNLV--Q 798

  Fly   287 PNSLAQEEQDF--FNQGSLGAGGNEKDQSG-----------KMSKDSILALYGSAPATHNPQMNF 338
            |::||...|..  :..|||...|.::..|.           :::..|:|...|:||.       .
Zfish   799 PSALAGLTQGSPGWKPGSLDLSGRQRSSSDPPNMHPPAPPLRVTSTSLLMPSGAAPP-------L 856

  Fly   339 GGFTGMAPGGYMHQQQQQQIPHQFMTPPNSVSMYNSPVMAAPNAFSNAAISSATAMSM------- 396
            ...|||     |.....|..|.|  .||.  ...|....|..| ||.:.:..:.::..
Zfish   857 AKATGM-----METMNMQPKPGQ--GPPG--QNINRATSADKN-FSKSTLMRSGSIERPGRCQRN 911

  Fly   397 --------GGSHGFTGAQFPST 410
                    ||....||...|:|
Zfish   912 HVNSKEVPGGPQNTTGQTLPAT 933

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8243	NP_610424.1	ArfGap	18..132	CDD:279720	46/117 (39%)
		COG5347	20..300	CDD:227651	83/396 (21%)
asap2a	XP_021322892.1	BAR_ASAP2	34..257	CDD:153326
		PH_ASAP	309..415	CDD:270071
		ArfGap	433..550	CDD:307528	46/117 (39%)
		ANK repeat	562..594	CDD:293786	0/31 (0%)
		ANK	<597..685	CDD:238125	11/87 (13%)
		ANK repeat	597..630	CDD:293786	2/32 (6%)
		ANK repeat	632..663	CDD:293786	3/30 (10%)
		SH3	945..1000	CDD:327375

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5347
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900