DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG8243 and Agap3

DIOPT Version :9

Sequence 1:NP_610424.1 Gene:CG8243 / 35890 FlyBaseID:FBgn0033349 Length:517 Species:Drosophila melanogaster
Sequence 2:XP_006236000.1 Gene:Agap3 / 362300 RGDID:1310751 Length:1093 Species:Rattus norvegicus


Alignment Length:204 Identity:68/204 - (33%)
Similarity:103/204 - (50%) Gaps:35/204 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly     5 NAGQRTKLIQEKCQTLLTQMLRDEDNKYCVDCDAKGPRWASWNLGMFLCIRCAGIHRNLGVHISR 69
            :|..:|:|..:.....:..:.....|.:||||:|..|.|||.|||..:||.|:||||:||.|:||
  Rat   831 SAKDKTRLGNQSTALAVQTVRTARGNSFCVDCEAPNPDWASLNLGALMCIECSGIHRHLGAHLSR 895

  Fly    70 VKSVNLDTWTPEQVISLQQMGNSRARAVYEAQLPDGFRRPQTDTA---LENFIRAKYEHKKYLAR 131
            |:|::||.|.||.:..:..|||:.|.:|:|..| ||:.:|..:..   .|.:||||||.|.:|| 
  Rat   896 VRSLDLDDWPPELLAVMTAMGNALANSVWEGAL-DGYSKPGPEACREEKERWIRAKYEQKLFLA- 958

  Fly   132 EWVPPSPPK-VDWAKE-----IDEEL--------ERQKRKKKSTQAQATLGLAGVAGGSGDKRLS 182
                |.|.. |...::     ::::|        ...|.:...|.            |.||.|.:
  Rat   959 ----PLPSSDVPLGQQLLRAVVEDDLRLLVMLLAHGSKEEVNETY------------GDGDGRTA 1007

  Fly   183 GSSASALKN 191
            ...:||:.|
  Rat  1008 LHLSSAMAN 1016

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG8243NP_610424.1 ArfGap 18..132 CDD:279720 52/116 (45%)
COG5347 20..300 CDD:227651 65/189 (34%)
Agap3XP_006236000.1 small_GTPase 309..474 CDD:197466
Centaurin_gamma 311..468 CDD:133303
PH_AGAP 584..827 CDD:241281
PH 587..>648 CDD:278594
ArfGap 855..960 CDD:279720 52/110 (47%)
Ank_2 971..1061 CDD:289560 10/58 (17%)
ANK 971..>1060 CDD:238125 10/58 (17%)
ANK repeat 971..1001 CDD:293786 3/41 (7%)
ANK repeat 1003..1034 CDD:293786 5/14 (36%)
ANK repeat 1036..1061 CDD:293786
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5347
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
32.810

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