Protein Alignment CG8243 and Arfgap2

DIOPT Version :10

• Sequence 1: NP_610424.1
• Gene: CG8243 / 35890
• FlyBaseID: FBgn0033349
• Length: 517
• Species: Drosophila melanogaster
• Sequence 2: XP_006234592.1
• Gene: Arfgap2 / 362162
• RGDID: 1306177
• Length: 534
• Species: Rattus norvegicus
• Alignment Length: 581
• Identity: 134/581 - (23%)
• Similarity: 216/581 - (37%)
• Gaps: 139/581 - (23%)

  Fly    14 QEKCQTLLTQMLRDEDNKYCVDCDAKGPRWASWNLGMFLCIRCAGIHRNLGVHISRVKSVNLDT- 77
            :.:.|||..::.....||.|.||.||.|.|||...|:||||.|:|:||:||||:|.::|..||:
  Rat     7 KSEIQTLFKRLRAIPTNKACFDCGAKSPSWASITYGVFLCIDCSGVHRSLGVHLSFIRSTELDSN 71

  Fly    78 WTPEQVISLQQMGNSRARAVYEAQLPDGFRRPQTDTALENFIRAKYEHK------KYLAREWVPP 136
            |:..|:..:|..||:.|.|.:...   |......:|...:.....|..|      ..|||.....
  Rat    72 WSWLQLRCMQVGGNANATAFFRQH---GCLANDANTKYNSRAAQMYREKIRQLGSTALARHGTDL 133

  Fly   137 SPPKVDWAKEIDEELERQKRKKKS------TQAQATLGLAGVAGGSGDKRLSGSSASALKNTPLP 195
                  |...::........||.|      |||.|....|....|:....|...|:|..:
  Rat   134 ------WIDNMNSAPSHSPEKKDSDFFTEHTQAPAWDTAATDPSGTQQPALPSESSSLAQ----- 187

  Fly   196 APLPKPKPN-QVGGCSPKTT-QRVQLNSSGVSSAGE--SDLLGLSSPTKPIVATNA-----SQDL 251
               |:|.|| .:.|.||:.: :.:.|::.|:||..|  |.::|...|........|     :|.:
  Rat   188 ---PEPGPNTDLLGTSPQASLESMYLSAKGLSSTRELKSSIIGKKKPAAAKKGLGAKKGLGAQKV 249

  Fly   252 QNESFTSFLSAESIA------------GQPDKPIGSNGDAA----------------NLMGSKPN 288
            .|:|||.......:|            .|.::.:.::...|                ||.|.|
  Rat   250 SNQSFTEIERQAQVAEKLREQQAADAKKQAEESMVASMRLAYQELQIDRKKEEKKLQNLEGKK-- 312

  Fly   289 SLAQEEQDFFNQGSLGAGG-------------NEKDQSGKMSKDSI-----LALYGSAPATH--N 333
               :|:.:....|.:....             .|...|.|.|:..:     :..:.|.|..:  |
  Rat   313 ---REQAERLGMGLVSRSSISHSVLSEMQMIEQETPLSAKSSRSQLDLFDDVGTFASGPPKYKDN 374

  Fly   334 PQMNFGGFTG------MAPGGYMHQQQQQQIPHQFMTP----PNSVSMYNSPVMAAPNAFSNAAI 388
            | .:.|...|      .|.|....::::.::....:.|    ..|.....|.:....::.:....
  Rat   375 P-FSLGETFGSRWDSDAAWGMDRVEEKEPEVTISSIRPISERTTSRREVESRISGLESSEARQKF 438

  Fly   389 SSATAMSMGGSHGFTGAQFPSTGGSPYAAAGQAAATNLMQ-TNQSILSGMPLFGAVPQQQQQHQQ 452
            :.|.|:|   |..|.|.:..|.         ..|.:.|.| :..|.:|...|||.|....
  Rat   439 AGAKAIS---SDMFFGREVDSE---------YEARSRLQQLSGSSAISSSDLFGDVDGAH----- 486

  Fly   453 QLQQQHHPQLGGLSMNLMQPLPSGLNIGQPPQG----AGGFAATGPTTSSVPSNLNQQFGN 509
                      ||.:::|...||:. :|.|..||    ||..|.   ..:.|.::|..::|:
  Rat   487 ----------GGGTVSLGNVLPTA-DIAQFKQGVKSVAGKMAV---LANGVMNSLQDRYGS 533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8243	NP_610424.1	COG5347	20..300	CDD:227651	85/329 (26%)
		ArfGap_SMAP	21..123	CDD:350068	37/102 (36%)
Arfgap2	XP_006234592.1	ArfGap_ArfGap2	5..124	CDD:350086	42/119 (35%)
		PLN03114	12..484	CDD:178661	118/506 (23%)
		YqiK	<256..>318	CDD:441869	8/66 (12%)