Protein Alignment CG8243 and Git

DIOPT Version :9

• Sequence 1: NP_610424.1
• Gene: CG8243 / 35890
• FlyBaseID: FBgn0033349
• Length: 517
• Species: Drosophila melanogaster
• Sequence 2: NP_610599.3
• Gene: Git / 36122
• FlyBaseID: FBgn0033539
• Length: 731
• Species: Drosophila melanogaster
• Alignment Length: 640
• Identity: 128/640 - (20%)
• Similarity: 213/640 - (33%)
• Gaps: 189/640 - (29%)

  Fly     9 RTKLIQEKCQTLLTQMLRDEDNKYCVDCDAKGPRWASWNLGMFLCIRCAGIHRNLGVHISRVKSV 73
            |:|:.:.|.: |.|::        |.||.|..|.|||.|.|:.||..|..:||:||.|||.|||:
  Fly    34 RSKMPRGKSR-LQTEV--------CGDCGAGDPSWASINRGILLCADCCSVHRSLGRHISIVKSL 89

  Fly    74 NLDTWTPEQVISLQQMGNSRARAVYEAQLPDG------------FRRPQTDTAL----ENFIRAK 122
            ....|.|..:..:..:....|.:|:|..|.||            :|:|....||    .:||:||
  Fly    90 RQGNWEPSVLNFVNSLNAHGANSVWEHHLLDGSTNSTGGKHVPRWRKPTPKDALHPTKSDFIKAK 154

  Fly   123 YEHKKYLAREWVPPSPPKVDWAKEIDEELERQKRKKKSTQAQAT--------------------- 166
            :.:..::.:..:.........|..:::||.||......|....|
  Fly   155 HVNLTFVLKPSLQDDDDGNGSAGCLEQELSRQLHASVRTSNLETSLRFLVQGADPNYYHEDKLST 219

  Fly   167 -LGLAGVAGGSGDKR---LSGSSASALKNTPLPAPLPKPKPNQ---------------------- 205
             |.:|...|.:....   :.|:..:||....: .||...:.|.
  Fly   220 PLHMAAKFGQASQIEMLLIYGADVNALDGNGM-TPLELARANNHNTIAERLLDAMYDVTDRIITF 283

  Fly   206 VGGCSPKTTQRVQLNSSGVSSAGESDLLGLSSPTKPIVATNASQDLQNESF-------------T 257
            :||..|.......:.....:.|..|:.|.::.....:|.....::|..:.:             |
  Fly   284 LGGKKPDHASGRHMIIPDANGADISEQLKIARGKLQLVPNKMFEELVMDLYDEVDRRECEAIWST 348

  Fly   258 SFLSAE--SIAGQPDKPIGS-----------NGDAANLMGSKPNSL--AQEEQDFFNQGSLGA-- 305
            |.|:|:  ::...|..|..|           ..:.|...|...:.|  |...|:..|...:.|
  Fly   349 STLNADHATVPFLPANPFLSATRNQGRQKLARFNRAEFTGLLTDVLVDAMRRQNMANLRPMDAPV 413

  Fly   306 GGNEKDQSGKMSKDSILALYGSAPATHNPQMN--------FGGFTGMAPGGYMHQQQQQQIPHQF 362
            .|::..||...:.:|:| |.......|:|.::        .......||   :....||.|.|
  Fly   414 AGHQSLQSLPYANNSML-LGSFEQGGHDPNLSDDEPIYDPVASDDDYAP---VPPMAQQAIVH-- 472

  Fly   363 MTPPNSVSMYNS----------------------PVMAAPNAFSNAAISSATAMSM--------- 396
             |||.|.:.:|.                      .::::.|....:..|||:..|:
  Fly   473 -TPPRSANSHNEMETLRKQLNDYKSEINQLKNVVQMLSSENTQLKSKFSSASNNSVYDEPLRIDL 536

  Fly   397 -----------------GGSHGFTGAQFPSTGGS--------------PYAAAGQAAATNLMQTN 430
                             |.::|.:|:...|:..|              |..|.|.....|.....
  Fly   537 SLSSPDTEHEPLSLPEGGTANGESGSSNDSSNQSTIKRPASMYERRLVPNVAKGNTDIRNTTSMY 601

  Fly   431 QSILSGMPLFGAVPQQQQQHQQQLQQQHHPQLGGLSMNLMQPLPSGLNIGQPPQG 485
            |....|.| ||    ::.:.:..|..:...:|    :..|||:|........|.|
  Fly   602 QMAGDGKP-FG----EEVKVRSDLVTRRLKEL----IRAMQPVPEDQKQSIAPHG 647

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8243	NP_610424.1	ArfGap	18..132	CDD:279720	41/129 (32%)
		COG5347	20..300	CDD:227651	77/370 (21%)
Git	NP_610599.3	ArfGap	48..164	CDD:279720	39/123 (32%)
		Ank_2	187..279	CDD:289560	11/92 (12%)
		ANK	<187..270	CDD:238125	11/83 (13%)
		ANK repeat	187..213	CDD:293786	2/25 (8%)
		ANK repeat	215..247	CDD:293786	5/31 (16%)
		ANK repeat	249..279	CDD:293786	3/30 (10%)
		GIT_SHD	314..342	CDD:285690	2/27 (7%)
		GIT	374..404	CDD:128828	5/29 (17%)
		GIT1_C	609..727	CDD:289013	11/48 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45464122
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5347
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740