Protein Alignment CG8243 and Asap

DIOPT Version :10

• Sequence 1: NP_610424.1
• Gene: CG8243 / 35890
• FlyBaseID: FBgn0033349
• Length: 517
• Species: Drosophila melanogaster
• Sequence 2: NP_001014504.1
• Gene: Asap / 35783
• FlyBaseID: FBgn0050372
• Length: 1155
• Species: Drosophila melanogaster
• Alignment Length: 636
• Identity: 133/636 - (20%)
• Similarity: 210/636 - (33%)
• Gaps: 226/636 - (35%)

  Fly     4 SNAGQRTKLIQ-EKCQTLLTQMLRDEDNKYCVDCDAKGP-RWASWNLGMFLCIRCAGIHRNLGVH 66
            :|......|:: :|......|:|...|.  |.||.::.. .|.|.|.|:.:||:|:|:||:||||
  Fly   414 ANPQMSPSLVELQKTVIRYVQLLPGNDR--CCDCGSRNDVTWISLNFGILVCIQCSGVHRDLGVH 476

  Fly    67 ISRVKSVNLDTWTPEQVISLQQMGNSRARAVYEAQLPDGFRRPQTDTALE---NFIRAKYEHKKY 128
            .||::|:.||..|...::..:.||||....:.||:|..|  :.|.::::|   :||||||..|:|
  Fly   477 HSRIQSLTLDNLTTANLLIARAMGNSTLNDIMEAKLGRG--KLQHESSMEERYDFIRAKYVAKRY 539

  Fly   129 LAREWVPPSPPKVD----------------WAKEID----------------------------- 148
            :.|.....:..:.|                ||:..|
  Fly   540 VMRTCSDDNDLRCDLEQAVVNADMSQLLQVWAEGADLTCCLPSSDAGETALHLAVLREMGSTLHI 604

  Fly   149 -EELERQKRKKKSTQAQATLGLAGVAGGS--------GDKR------LSGSSASALKNTPLPAPL 198
             :.|.:....|...:|....||..|.|.:        .|:|      |...:...|||:.....|
  Fly   605 VDFLIQNMPPKGLNKATNPAGLLDVTGKNTALHLCALHDRRECMKLLLRSGADYELKNSQNKTAL 669

  Fly   199 PKPK-------------------------------PNQ-------------------------VG 207
            ...|                               ||:                         .|
  Fly   670 DIAKEMGHNSCRELIECAIKREKSAFDHINTDWNLPNEDGSTDFSDDETVIDERKSRSRPPSFAG 734

  Fly   208 GCSP------KTTQRVQLNSSGVSSAGESDLL---GLSSPTKPIVATNASQDLQNESFTSFLSAE 263
            |.||      .|...:|.:||.:::.......   ||.|.|.. ..|:..|.:   |...:|.:.
  Fly   735 GDSPVLRSRSSTCDSIQSSSSPIANCPSRQFTLPSGLPSYTHS-AGTSPKQHI---SVGQYLGSA 795

  Fly   264 SIAGQPDKPIGSNGDAANLMGSKPNSLAQEE----QDFFN-QGSLG--AGGNEKDQS-------- 313
            :       .:|.||....  ||.|:|.:.:.    ::..| |..||  ..|..|..|
  Fly   796 T-------NVGGNGPGNG--GSSPSSASSQSVRAARNSLNMQSDLGGHVTGARKSTSTANMNSLK 851

  Fly   314 ---------GKMSKDSILALYGSAPATHNPQMNFGGFTGMAPGGYMHQQQQQQIPHQFMTPPNSV 369
                     |.:...|..:.||:.|   :|..:...|.........|:.|...:  .:.|.|:..
  Fly   852 KRTAPAPPPGTLGSASSSSFYGTLP---HPPRHSQNFDASDIRAINHKNQSLDV--AYGTLPHLR 911

  Fly   370 SMYNSPVMAAPNAFSNAAISSATAMSMGGSHGFTGAQFPSTGGSPYAAAGQAAATNLMQTNQSIL 434
            |:.:||                   ..||.:|:..:|.|...|:              .:|.|::
  Fly   912 SVESSP-------------------RGGGGYGYGVSQDPGGSGN--------------GSNNSLM 943

  Fly   435 SGMPLFGAVPQQQQQHQQQLQQQHHPQLGGLSMNLMQPLPSGLNIGQPPQG 485
            ..|..||                |.....|.|:|....| :|..:..||.|
  Fly   944 PAMTTFG----------------HKRSPSGESLNRNIHL-AGAKLVLPPTG 977

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8243	NP_610424.1	COG5347	20..300	CDD:227651	90/413 (22%)
		ArfGap_SMAP	21..123	CDD:350068	40/105 (38%)
Asap	NP_001014504.1	BAR_ASAPs	35..249	CDD:153288
		PH_ASAP	302..410	CDD:270071
		ArfGap_ASAP	425..541	CDD:350063	45/119 (38%)
		ANKYR	<573..709	CDD:440430	18/135 (13%)
		ANK repeat	586..622	CDD:293786	3/35 (9%)
		ANK repeat	624..662	CDD:293786	8/37 (22%)
		Vac17	<706..>788	CDD:435863	15/85 (18%)
		SH3_ASAP	1095..1149	CDD:212755