DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG8243 and Agap1

DIOPT Version :9

Sequence 1:NP_610424.1 Gene:CG8243 / 35890 FlyBaseID:FBgn0033349 Length:517 Species:Drosophila melanogaster
Sequence 2:NP_835220.1 Gene:Agap1 / 347722 MGIID:2653690 Length:857 Species:Mus musculus


Alignment Length:133 Identity:56/133 - (42%)
Similarity:80/133 - (60%) Gaps:9/133 - (6%)


- Green bases have known domain annotations that are detailed below.


  Fly     2 SSSNAGQRTKLIQEKCQTLLTQMLRD-EDNKYCVDCDAKGPRWASWNLGMFLCIRCAGIHRNLGV 65
            ||.|..:.|    .:.:.:..|.:|: ..|.:|||||.:.|.|||.|||..:||.|:|||||||.
Mouse   596 SSKNKSRLT----SQSEAMALQSIRNMRGNSHCVDCDTQNPNWASLNLGALMCIECSGIHRNLGT 656

  Fly    66 HISRVKSVNLDTWTPEQVISLQQMGNSRARAVYEAQLPDGFRRPQTDTA---LENFIRAKYEHKK 127
            |:|||:|::||.|..|.:..:..:||..|.:|:| :...|..:|..|:.   .|.:||||||.|.
Mouse   657 HLSRVRSLDLDDWPMELIKVMSSIGNELANSVWE-EGSQGRTKPSLDSTREEKERWIRAKYEQKL 720

  Fly   128 YLA 130
            :||
Mouse   721 FLA 723

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG8243NP_610424.1 ArfGap 18..132 CDD:279720 52/117 (44%)
COG5347 20..300 CDD:227651 52/115 (45%)
Agap1NP_835220.1 Small GTPase-like 66..276
Centaurin_gamma 72..229 CDD:133303
RAS 73..235 CDD:214541
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 267..342
PH_AGAP 344..592 CDD:241281
PH 347..>411 CDD:278594
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 407..431
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 497..547
ArfGap 611..725 CDD:279720 52/114 (46%)
Ank_2 736..826 CDD:289560
ANK 736..>825 CDD:238125
ANK repeat 768..799 CDD:293786
ANK 1 768..797
ANK 2 801..830
ANK repeat 801..826 CDD:293786
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5347
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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