Protein Alignment CG8243 and AGFG2

DIOPT Version :9

• Sequence 1: NP_610424.1
• Gene: CG8243 / 35890
• FlyBaseID: FBgn0033349
• Length: 517
• Species: Drosophila melanogaster
• Sequence 2: XP_005250363.1
• Gene: AGFG2 / 3268
• HGNCID: 5177
• Length: 492
• Species: Homo sapiens
• Alignment Length: 532
• Identity: 129/532 - (24%)
• Similarity: 197/532 - (37%)
• Gaps: 150/532 - (28%)

  Fly    30 NKYCVDCDAKGPRWASWNLGMFLCIRCAGIHRNLG-VHISRVKSVNLDTWTPEQVISLQQMGNSR 93
            |::|.:|..:|..:....:|.|:|..|:|:.|.|. .|  ||||:::.|:|..:|:.||..||..
Human    44 NRHCFECAQRGVTYVDITVGSFVCTTCSGLLRGLNPPH--RVKSISMTTFTEPEVVFLQSRGNEV 106

  Fly    94 ARAV----YEAQ---LPDGFRRPQTDTALENFIRAKYEHKKYLAREWVPPS-------------- 137
            .|.:    ::|:   :||. |.||   .::.|::.|||.|::    :|||.
Human   107 CRKIWLGLFDARTSLVPDS-RDPQ---KVKEFLQEKYEKKRW----YVPPDQVKGPTYTKGSAST 163

  Fly   138 -------------------PPKVDWAKEIDEELERQKRKKKSTQAQATLGLAGVAGGSGDKRLSG 183
                               .|.:..|.....:...|...:.| ||::|    .....|..|:.|.
Human   164 PVQGSIPEGKPLRTLLGDPAPSLSVAASTSSQPVSQSHARTS-QARST----QPPPHSSVKKAST 223

  Fly   184 SSASALKNTPLPAPLPKPK----PNQVGGCSPKTTQRVQLNSSGVSSAGESDLLGLSSP------ 238
            ...:.:...|..||...|.    | ..||.:|  :|....|....||...|.:.|...|
Human   224 DLLADIGGDPFAAPQMAPAFAAFP-AFGGQTP--SQGGFANFDAFSSGPSSSVFGSLPPAGQASF 285

  Fly   239 -TKPIVATNASQDLQNESFTSFLSAESIAGQPDKPIGSNGDAANLMGSKPNSLAQEEQDFFNQGS 302
             .:|   |.|:..:..||: ||.|::.      .|.|:...|.   .|:||||| :...|...|.
Human   286 QAQP---TPAASRMLTESY-SFGSSQG------TPFGATPLAP---ASQPNSLA-DVGSFLGPGV 336

  Fly   303 LGAGGNEKDQSGKMSKDSILALYGSAPATHNPQMNFGG--FTGMAPGGYMHQQQQQQIPHQFMTP 365
            ..||          ...|:..:.|..|...:..|..||  .||:|.|.:              |.
Human   337 PAAG----------VPSSLFGMAGQVPPLQSVTMGGGGGSSTGLAFGAF--------------TN 377

  Fly   366 PNSVSMYNSPVMAAPNAFSNAAISSATAMSMGGS-HGFTGAQFPSTGGSPYAAAGQAAATNLMQT 429
            |.:.....|| :.:.|.|....::......|..: .||..| .|.||.  :|::..|
Human   378 PFTAPAAQSP-LPSTNPFQPNGLAPGPGFGMSSAGPGFPQA-VPPTGA--FASSFPA-------- 430

  Fly   430 NQSILSGMPLF-GAVPQQQQQH--------QQQLQQQHHPQLGGLSMNLMQPLPSGLNIGQPPQG 485
                    ||| ...|..|||:        ..:|.|:...|..|:|.|.....||
Human   431 --------PLFPPQTPLVQQQNGSSFGDLGSAKLGQRPLSQPAGISTNPFMTGPS---------- 477

  Fly   486 AGGFAATGPTTS 497
            :..||:..|||:
Human   478 SSPFASKPPTTN 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8243	NP_610424.1	ArfGap	18..132	CDD:279720	35/109 (32%)
		COG5347	20..300	CDD:227651	81/321 (25%)
AGFG2	XP_005250363.1	ArfGap	40..147	CDD:295313	35/112 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5347
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810