DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8243 and Agap1

DIOPT Version :9

Sequence 1:	NP_610424.1	Gene:	CG8243 / 35890	FlyBaseID:	FBgn0033349	Length:	517	Species:	Drosophila melanogaster
Sequence 2:	XP_038939665.1	Gene:	Agap1 / 316611	RGDID:	1309244	Length:	1428	Species:	Rattus norvegicus

Alignment Length:	133	Identity:	56/133 - (42%)
Similarity:	80/133 - (60%)	Gaps:	9/133 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SSSNAGQRTKLIQEKCQTLLTQMLRD-EDNKYCVDCDAKGPRWASWNLGMFLCIRCAGIHRNLGV 65
            ||.|..:.|    .:.:.:..|.:|: ..|.:|||||.:.|.|||.|||..:||.|:|||||||.
  Rat  1167 SSKNKSRLT----SQSEAMALQSIRNMRGNSHCVDCDTQNPNWASLNLGALMCIECSGIHRNLGT 1227

  Fly    66 HISRVKSVNLDTWTPEQVISLQQMGNSRARAVYEAQLPDGFRRPQTDTA---LENFIRAKYEHKK 127
            |:|||:|::||.|..|.:..:..:||..|.:|:| :...|..:|..|:.   .|.:||||||.|.
  Rat  1228 HLSRVRSLDLDDWPMELIKVMSSIGNELANSVWE-EGSQGRTKPSLDSTREEKERWIRAKYEQKL 1291

  Fly   128 YLA 130
            :||
  Rat  1292 FLA 1294

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8243	NP_610424.1	ArfGap	18..132	CDD:279720	52/117 (44%)
CG8243	NP_610424.1	COG5347	20..300	CDD:227651	52/115 (45%)
Agap1	XP_038939665.1	Centaurin_gamma	561..722	CDD:133303
		PH_AGAP	837..>911	CDD:241281
		PH-like	<1123..1163	CDD:418428
		ArfGap_AGAP2	1180..1288	CDD:350078	47/108 (44%)
		ANK repeat	1304..1332	CDD:293786
		Ank_2	1307..1397	CDD:403870
		ANK repeat	1339..1370	CDD:293786
		ANK repeat	1372..1397	CDD:293786
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5347
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810