DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8243 and Adap1

DIOPT Version :9

Sequence 1:	NP_610424.1	Gene:	CG8243 / 35890	FlyBaseID:	FBgn0033349	Length:	517	Species:	Drosophila melanogaster
Sequence 2:	NP_766311.2	Gene:	Adap1 / 231821	MGIID:	2442201	Length:	374	Species:	Mus musculus

Alignment Length:	134	Identity:	56/134 - (41%)
Similarity:	80/134 - (59%)	Gaps:	12/134 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 AGQRTKLIQEKCQTLLTQMLRDEDNKYCVDCDAKGPRWASWNLGMFLCIRCAGIHRNLGVHISRV 70
            ||:|.:.:.|    |||:    ..|..|.||.|..|.|||:.||:|:|:.|:|||||: ..:|:|
Mouse     2 AGERRRALLE----LLTR----PGNTRCADCGAPDPDWASYTLGVFICLSCSGIHRNI-PQVSKV 57

  Fly    71 KSVNLDTWTPEQVISLQQMGNSRARAVYEAQLPDGFRRPQ-TDTAL--ENFIRAKYEHKKYLARE 132
            |||.||.|...||..:...||..|||.:|:::|..:.||. :|..|  |.:||||||.::::..|
Mouse    58 KSVRLDAWDEAQVEFMASHGNEAARATFESKVPPFYYRPTFSDCQLLREQWIRAKYERQEFVHVE 122

  Fly   133 WVPP 136
            ...|
Mouse   123 KQEP 126

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8243	NP_610424.1	ArfGap	18..132	CDD:279720	50/116 (43%)
CG8243	NP_610424.1	COG5347	20..300	CDD:227651	52/120 (43%)
Adap1	NP_766311.2	ArfGap	10..126	CDD:214518	52/124 (42%)
		PH1_ADAP	130..238	CDD:270072
		PH2_ADAP	252..357	CDD:241282
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5347
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810