Protein Alignment CG8243 and Agfg2

DIOPT Version :9

• Sequence 1: NP_610424.1
• Gene: CG8243 / 35890
• FlyBaseID: FBgn0033349
• Length: 517
• Species: Drosophila melanogaster
• Sequence 2: NP_001290195.1
• Gene: Agfg2 / 231801
• MGIID: 2443267
• Length: 490
• Species: Mus musculus
• Alignment Length: 522
• Identity: 128/522 - (24%)
• Similarity: 201/522 - (38%)
• Gaps: 132/522 - (25%)

  Fly    30 NKYCVDCDAKGPRWASWNLGMFLCIRCAGIHRNLG-VHISRVKSVNLDTWTPEQVISLQQMGNSR 93
            |::|.:|..:|..:....:|.|:|..|:|:.|.|. .|  ||||:::.|:|..:|:.||..||..
Mouse    44 NRHCFECAQRGVTYVDITVGSFVCTTCSGLLRGLNPPH--RVKSISMTTFTEPEVLFLQSRGNEV 106

  Fly    94 ARAV----YEAQ---LPDGFRRPQTDTALENFIRAKYEHKKYLAREWVPPSPPKVDWAKEIDEEL 151
            .|.:    ::|:   :||. |.||   .::.|::.|||.|::    :|||            |::
Mouse   107 CRKIWLGLFDARTSLIPDS-RDPQ---KVKEFLQEKYEKKRW----YVPP------------EQV 151

  Fly   152 ERQKRKKKSTQAQATLGLAGVAGGSGDKRLSGSSASALKNTPLPAPLPKPKPNQVGGCSPKTTQR 216
            :.....|.|..|....|  .|..|...:.|.|....:|.:       |....:|.|..|
Mouse   152 KGPSYSKGSVSATPVQG--SVPEGKPIRTLLGDPVPSLSD-------PASTSSQPGSQS------ 201

  Fly   217 VQLNSSGVSSAGESDLLGLSSPTKPIVATNASQDLQNESFTSFLSAESIAGQPDKPIG------- 274
             |..||  |.|..|.....||..|  .:|:...|:..:.|.:.....:.|..|...:|
Mouse   202 -QARSS--SQARSSQPPSHSSTKK--ASTDLLADIGGDPFAAPQVVPAFASFPGFGVGQTPAHGG 261

  Fly   275 -------SNGDAANLMGSKPNSLAQEEQDFFNQGSLGAG----GNEKDQSGKMSKDSILALYGSA 328
                   |:..:::..||.|.|:   :..|..|.:..|.    |:....||:||      .:|.|
Mouse   262 FANFDAFSSSPSSSTFGSLPPSV---QAPFQAQPTPAANRMLTGSYSFGSGQMS------AFGVA 317

  Fly   329 PATHNPQMN----FGGFTG--MAPGGYMHQQQQQQIPHQFMTPPNSVSMYNSPVMAAPNAFSNAA 387
            |.....|.|    .||..|  ||.||         :|......|:.|....|.|         ..
Mouse   318 PLAAASQPNNLADVGGLLGPRMAAGG---------LPGSVFGMPSQVPALQSAV---------PG 364

  Fly   388 ISSATAMSMGGSHGFTG-------AQFPSTGGSPYAAAGQAAAT--NLMQTNQSILSGMPLFGA- 442
            :|.:..:..|   .:|.       ||.|||  :|:...|.|:..  .:......:|..:|..||
Mouse   365 VSGSGGLPFG---AYTNPFATPAQAQLPST--NPFQPNGLASGPGFGMSSVRPGLLQPVPPSGAF 424

  Fly   443 --------VPQQQQQHQQQLQQQHHPQLGGLSMNLM--QPL--PSGLNIGQPPQGAGGFAATGPT 495
                    .|.|    .....||:....|.|..:.:  :||  |:|::......|:..||:..||
Mouse   425 ASPFSAPVFPTQ----AGLADQQNGSSFGDLGTSKLGQRPLSQPAGISTNPFMTGSSAFASKPPT 485

  Fly   496 TS 497
            |:
Mouse   486 TN 487

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8243	NP_610424.1	ArfGap	18..132	CDD:279720	35/109 (32%)
		COG5347	20..300	CDD:227651	73/291 (25%)
Agfg2	NP_001290195.1	ArfGap	40..152	CDD:295313	39/129 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5347
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810