DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8243 and Adap2

DIOPT Version :9

Sequence 1:	NP_610424.1	Gene:	CG8243 / 35890	FlyBaseID:	FBgn0033349	Length:	517	Species:	Drosophila melanogaster
Sequence 2:	NP_742145.1	Gene:	Adap2 / 216991	MGIID:	2663075	Length:	381	Species:	Mus musculus

Alignment Length:	122	Identity:	48/122 - (39%)
Similarity:	73/122 - (59%)	Gaps:	6/122 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 QEKCQTLLTQMLR--DEDNKYCVDCDAKGPRWASWNLGMFLCIRCAGIHRNLGVHISRVKSVNLD 76
            :|:.:..|.::|:  ...|.:|.||.|..|.|||:.||:|:|:.|:|:|||. ..||:||||.||
Mouse     4 RERNKKRLLELLQAAGTGNGHCADCGAADPDWASYKLGIFICLHCSGVHRNF-PDISKVKSVRLD 67

  Fly    77 TWTPEQVISLQQMGNSRARAVYEAQLPDGFRRPQTDTAL---ENFIRAKYEHKKYLA 130
            .|....|..:...||...:|.:||::|..:..||.:..|   |.:||||||.:::.|
Mouse    68 FWDDSMVEFMTHHGNLNVKAKFEARVPAFYYVPQANDCLVLKEQWIRAKYERQEFTA 124

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8243	NP_610424.1	ArfGap	18..132	CDD:279720	47/118 (40%)
CG8243	NP_610424.1	COG5347	20..300	CDD:227651	47/116 (41%)
Adap2	NP_742145.1	ArfGap	9..123	CDD:279720	46/114 (40%)
		PH1_ADAP	133..241	CDD:270072
		PH	135..231	CDD:278594
		PH2_ADAP	255..362	CDD:241282
		PH	258..361	CDD:278594
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5347
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810