DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8243 and Agap2

DIOPT Version :9

Sequence 1:	NP_610424.1	Gene:	CG8243 / 35890	FlyBaseID:	FBgn0033349	Length:	517	Species:	Drosophila melanogaster
Sequence 2:	XP_006513621.1	Gene:	Agap2 / 216439	MGIID:	3580016	Length:	1342	Species:	Mus musculus

Alignment Length:	132	Identity:	56/132 - (42%)
Similarity:	78/132 - (59%)	Gaps:	8/132 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 SSNAGQRTKLIQEKCQTLLTQMLRD-EDNKYCVDCDAKGPRWASWNLGMFLCIRCAGIHRNLGVH 66
            ||....||   ..:.:.:..|.:|: :.|..||||.|..|.|||.|||..:||.|:|||||||.|
Mouse   912 SSKVKLRT---DSQSEAVAIQAIRNAKGNSTCVDCGAPNPTWASLNLGALICIECSGIHRNLGTH 973

  Fly    67 ISRVKSVNLDTWTPEQVISLQQMGNSRARAVYEAQLPDGFRRPQTDTA---LENFIRAKYEHKKY 128
            :|||:|::||.|..|..:.|..:||..|..|:|:. ..|..:|..|::   .|::||||||...:
Mouse   974 LSRVRSLDLDDWPRELTLVLTAIGNDTANRVWESD-TRGRAKPTRDSSREERESWIRAKYEQLLF 1037

  Fly   129 LA 130
            ||
Mouse  1038 LA 1039

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8243	NP_610424.1	ArfGap	18..132	CDD:279720	52/117 (44%)
CG8243	NP_610424.1	COG5347	20..300	CDD:227651	52/115 (45%)
Agap2	XP_006513621.1	PHA03247	<52..320	CDD:223021
		Centaurin_gamma	401..560	CDD:133303
		PH_AGAP	668..908	CDD:241281
		ArfGap_AGAP	926..1033	CDD:350065	48/107 (45%)
		SelP_N	<1136..1188	CDD:368014
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5347
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810