DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG8243 and Agap3

DIOPT Version :9

Sequence 1:NP_610424.1 Gene:CG8243 / 35890 FlyBaseID:FBgn0033349 Length:517 Species:Drosophila melanogaster
Sequence 2:XP_006535736.1 Gene:Agap3 / 213990 MGIID:2183446 Length:1093 Species:Mus musculus


Alignment Length:205 Identity:70/205 - (34%)
Similarity:104/205 - (50%) Gaps:37/205 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly     5 NAGQRTKLIQEKCQTLLTQMLRD-EDNKYCVDCDAKGPRWASWNLGMFLCIRCAGIHRNLGVHIS 68
            :|..:|:|..:. ..|..|.:|. ..|..|:||:|..|.|||.|||..:||.|:||||:||.|:|
Mouse   831 SAKDKTRLGNQN-TALAVQAVRTVRGNSLCIDCEAPNPDWASLNLGALMCIECSGIHRHLGAHLS 894

  Fly    69 RVKSVNLDTWTPEQVISLQQMGNSRARAVYEAQLPDGFRRPQTDTA---LENFIRAKYEHKKYLA 130
            ||:|::||.|.||.:..:..|||:.|.:|:|..| ||:.:|..:..   .|.:||||||.|.:||
Mouse   895 RVRSLDLDDWPPELLAVMTAMGNALANSVWEGAL-DGYSKPGPEACREEKERWIRAKYEQKLFLA 958

  Fly   131 REWVPPSPPK-VDWAKE-----IDEEL--------ERQKRKKKSTQAQATLGLAGVAGGSGDKRL 181
                 |.|.. |...::     ::::|        ...|.:...|.            |.||.|.
Mouse   959 -----PLPSSDVPLGQQLLRAVVEDDLRLLVMLLAHGSKEEVNETY------------GDGDGRT 1006

  Fly   182 SGSSASALKN 191
            :...:||:.|
Mouse  1007 ALHLSSAMAN 1016

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG8243NP_610424.1 ArfGap 18..132 CDD:279720 54/117 (46%)
COG5347 20..300 CDD:227651 67/190 (35%)
Agap3XP_006535736.1 Centaurin_gamma 310..467 CDD:133303
PH_AGAP 583..827 CDD:241281
PRK07003 <645..>756 CDD:235906
ArfGap_AGAP3 843..952 CDD:350080 49/109 (45%)
Ank_2 971..1061 CDD:372319 10/58 (17%)
ANK repeat 971..1001 CDD:293786 3/41 (7%)
ANK repeat 1003..1034 CDD:293786 5/14 (36%)
ANK repeat 1036..1061 CDD:293786
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5347
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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