DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG8243 and Arap2

DIOPT Version :9

Sequence 1:NP_610424.1 Gene:CG8243 / 35890 FlyBaseID:FBgn0033349 Length:517 Species:Drosophila melanogaster
Sequence 2:NP_848494.2 Gene:Arap2 / 212285 MGIID:2684416 Length:1703 Species:Mus musculus


Alignment Length:316 Identity:84/316 - (26%)
Similarity:132/316 - (41%) Gaps:46/316 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly    15 EKCQTLLTQMLRD----------EDNKYCVDCDAKGPRWASWNLGMFLCIRCAGIHRNLGVHISR 69
            |..|..:.:.|.|          |.|:.|.||.|..|.|||.||.:.:|.:|||.||:||...|:
Mouse   670 EAVQQSIAETLSDYEVAEKIWFNESNRSCADCKAPDPDWASINLCVVICKKCAGQHRSLGPKDSK 734

  Fly    70 VKSVNLDT--WTPEQVISLQQMGNSRARAVYEAQLPDGFRRPQTDTALE---NFIRAKYEHKKYL 129
            |:|:.:|.  |:.|.:.....:||.||...:...|... ...|.|:.:|   |||..||:..|: 
Mouse   735 VRSLKMDASIWSNELIELFIVIGNKRANDFWAGNLQKD-EELQVDSPVEKRKNFITQKYKEGKF- 797

  Fly   130 AREWVPPSPPKVDWAKEIDEELERQKRKKKSTQAQATL-GLAGVAGGSGDK------RLSGSSAS 187
             |:.:..|..|    :|:::.|.....|....:..|.| ..|.|...:||.      .|:..:..
Mouse   798 -RKTLLASLTK----EELNKALCAAVVKPDVLETMALLFSGADVMCATGDPVHSTPYLLAKKAGQ 857

  Fly   188 ALKNTPLP----APLPKPKPNQVGGCSPKTTQRVQLNSSGVSSAGESDLLGLSSPTKPIVATNAS 248
            :|:...|.    :..|:...:..||.|....|...|......:|..:.  .:||..|.:..||..
Mouse   858 SLQMEFLYHNKFSDFPQYDAHFEGGSSQDAAQSSFLCDFLYQTAAAAS--RVSSEKKLLEDTNKK 920

  Fly   249 QDLQNESFTSFLSAESIAGQPDKPIGSNGDAANLMGSKPNSLAQEEQDFF-NQGSL 303
            ..:....|.|:.       :.|:....|| ..|:  |:...||..::||: |.|.:
Mouse   921 WCVLEGGFLSYY-------ENDRCTTPNG-TINI--SEVICLAVHKEDFYLNTGPI 966

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG8243NP_610424.1 ArfGap 18..132 CDD:279720 43/128 (34%)
COG5347 20..300 CDD:227651 80/306 (26%)
Arap2NP_848494.2 SAM_Arap1,2,3 6..68 CDD:188889
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 84..132
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 191..232
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 286..319
PH1_ARAP 482..573 CDD:270073
PH2_ARAP 583..673 CDD:270074 1/2 (50%)
ArfGap_ARAP2 678..798 CDD:350081 42/122 (34%)
PH3_ARAP 890..1000 CDD:270076 20/89 (22%)
PH-like 1013..1108 CDD:388408
RhoGAP_ARAP 1112..1291 CDD:239850
RA_ARAP2 1323..1420 CDD:340747
PH-like 1426..1537 CDD:388408
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1633..1670
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1684..1703
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5347
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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