Protein Alignment CG8243 and Asap2

DIOPT Version :9

• Sequence 1: NP_610424.1
• Gene: CG8243 / 35890
• FlyBaseID: FBgn0033349
• Length: 517
• Species: Drosophila melanogaster
• Sequence 2: XP_006515110.1
• Gene: Asap2 / 211914
• MGIID: 2685438
• Length: 1003
• Species: Mus musculus
• Alignment Length: 586
• Identity: 120/586 - (20%)
• Similarity: 199/586 - (33%)
• Gaps: 164/586 - (27%)

  Fly     5 NAGQRTKLIQEKCQTLLTQMLRDEDNKYCVDCDAKGPRWASWNLGMFLCIRCAGIHRNLGVHISR 69
            |.|: ..::||..:.:::::.|...|..|.||.|..|.|.|.|||:..||.|:||||.||||.||
Mouse   412 NTGE-NNIVQELTKEIISEVQRMTGNDVCCDCGAPDPTWLSTNLGILTCIECSGIHRELGVHYSR 475

  Fly    70 VKSVNLDTWTPEQVISLQQMGNSRARAVYEAQLP--DGFR-RPQTD-TALENFIRAKYEHKKYLA 130
            ::|:.||.....:::..:.:||:....:.|..||  |..: .|.:| .|.:::|.|||..::|..
Mouse   476 MQSLTLDVLGTSELLLAKNIGNAGFNEIMECCLPSEDPVKPNPGSDMIARKDYITAKYMERRYAR 540

  Fly   131 REWVPPSPPKVDWAKEIDEELERQKRKKKSTQAQATLGLAGVAGGSGDKRLSGSSASALKNTPLP 195
            ::       ..|.|.::....|..|          |..:.|:.....|      .....:..||
Mouse   541 KK-------HADTAAKLHSLCEAVK----------TRDIFGLLQAYAD------GVDLTEKIPL- 581

  Fly   196 APLPKPKPNQVGGCSP---------KTTQRVQLNSSG--VSSAGESD--------------LLGL 235
                      ..|..|         ::..|..|:...  |.::|..|              |...
Mouse   582 ----------ANGHEPDETALHLAVRSVDRTSLHIVDFLVQNSGNLDKQTGKGSTALHYCCLTDN 636

  Fly   236 SSPTKPIVATNASQDLQNES--------------FTSFLSAESIAGQPDKPI------------- 273
            :...|.::...||.::.|||              ....|..::::|:.:..:
Mouse   637 AECLKLLLRGKASIEIANESGETPLDIAKRLKHEHCEELLTQALSGRFNSHVHVEYEWRLLHEDL 701

  Fly   274 -GSNGDAANLMGSKPNSLAQEEQDFFNQGSLGAGGNEKDQSGKMSKDSILALYGSAPATHNPQMN 337
             .|:.|....:...||........|:..|           |.:...:::.....:|..|.:.|..
Mouse   702 DESDDDVDEKLQPSPNRREDRPVSFYQLG-----------SSQFQSNAVSLARDTANLTKDKQRG 755

  Fly   338 FG-------GFTGMAPGGYMHQQQQQQIPHQFMTPPNSVSMYNSPVMAAP----NAFSNAAISSA 391
            ||       .:..:..|                :||:|.|:..|...|.|    |.......:||
Mouse   756 FGPSILQNETYGAILSG----------------SPPSSQSIPPSTTSAPPLPPRNVGKVQTATSA 804

  Fly   392 TAMSMGGSHGFTGAQFPSTGGSPYAAAGQAAATNLMQTNQSILSGMPLFGAVPQQQQQHQQQLQQ 456
            ..:....|.|..|.....:.....|.........:..||       ||....|....:....|:.
Mouse   805 NTLWKTNSVGVDGISRQRSSSDLPAVHPPLPPLRVTSTN-------PLTTTPPPPVAKTSGTLEA 862

  Fly   457 QHHPQLG---GLSMNLMQPLP-------------SG-------LNIGQPPQGAGGFAATGPTTSS 498
            .:.|...   |.|.:...|||             ||       .|.|||    .|..|:||.:::
Mouse   863 MNQPSKSSQPGTSQSKPPPLPPQPPSRLPQKKPASGTDKPTPLTNKGQP----RGPEASGPLSNA 923

  Fly   499 V 499
            :
Mouse   924 M 924

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8243	NP_610424.1	ArfGap	18..132	CDD:279720	42/117 (36%)
		COG5347	20..300	CDD:227651	72/336 (21%)
Asap2	XP_006515110.1	BAR_ASAP2	34..248	CDD:153326
		PH_ASAP	300..406	CDD:270071
		ArfGap_ASAP2	422..544	CDD:350074	42/128 (33%)
		ANK repeat	553..585	CDD:293786	7/58 (12%)
		ANK repeat	589..621	CDD:293786	5/31 (16%)
		Ank_2	592..676	CDD:372319	12/83 (14%)
		ANK repeat	623..654	CDD:293786	4/30 (13%)
		SH3_ASAP2	945..1000	CDD:212899

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5347
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810