DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8243 and git-1

DIOPT Version :9

Sequence 1:	NP_610424.1	Gene:	CG8243 / 35890	FlyBaseID:	FBgn0033349	Length:	517	Species:	Drosophila melanogaster
Sequence 2:	NP_509761.2	Gene:	git-1 / 181253	WormBaseID:	WBGene00008805	Length:	670	Species:	Caenorhabditis elegans

Alignment Length:	180	Identity:	44/180 - (24%)
Similarity:	71/180 - (39%)	Gaps:	35/180 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 LLTQMLRDEDNKYCVDCDAKGPRWASWNLGMFLCIRCAGIHRNLGVHISRVKSVNLDTWTPEQVI 84
            |:|.:    :.|.|.||..|...|||...|..:|..|...|..||..:|.::.:....|..|.:.
Worm     9 LITSL----EQKECDDCGKKEVEWASVKKGTVICSECFCFHSYLGPSVSYLRHLRKSAWDEEHIR 69

  Fly    85 SLQQMGNSRARAVYEAQLPDG---FRRPQTDT---ALENFIRAKYEHKKYLAREWVPPSPPKVDW 143
            .:..:..|....::|:.|.:|   |::|....   ..|.|::.|||...:         .||
Worm    70 LVHALNTSNTNMIWESALYEGSTKFQKPMAQDPSHIKEQFVKEKYEKLTF---------QPK--- 122

  Fly   144 AKEIDEELERQKRKK-----KSTQAQATLGLAGVAGG-------SGDKRL 181
             :..||:||....::     :|..|..||.|..:...       :||..|
Worm   123 -RGKDEDLENSLNRQLIACARSDFAHVTLRLIALGADVNYPDPETGDTAL 171

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8243	NP_610424.1	ArfGap	18..132	CDD:279720	30/117 (26%)
CG8243	NP_610424.1	COG5347	20..300	CDD:227651	44/180 (24%)
git-1	NP_509761.2	ArfGap	7..127	CDD:214518	32/134 (24%)
		ANK	<122..212	CDD:238125	13/54 (24%)
		Ank_5	152..207	CDD:290568	4/20 (20%)
		ANK repeat	165..197	CDD:293786	3/7 (43%)
		GIT	264..294	CDD:128828
		GIT	326..356	CDD:128828
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5347
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900