Protein Alignment CG8243 and W09D10.1

DIOPT Version :9

• Sequence 1: NP_610424.1
• Gene: CG8243 / 35890
• FlyBaseID: FBgn0033349
• Length: 517
• Species: Drosophila melanogaster
• Sequence 2: NP_499364.1
• Gene: W09D10.1 / 176499
• WormBaseID: WBGene00012359
• Length: 495
• Species: Caenorhabditis elegans
• Alignment Length: 546
• Identity: 182/546 - (33%)
• Similarity: 239/546 - (43%)
• Gaps: 115/546 - (21%)

  Fly    14 QEKCQTLLTQMLRDEDNKYCVDCDAKGPRWASWNLGMFLCIRCAGIHRNLGVHISRVKSVNLDTW 78
            ||:.|..|..||::|:||||.||.||.||||:||||:|:||||||||||||||||:|:|||||:|
 Worm    13 QERLQGFLLDMLKEEENKYCADCQAKTPRWAAWNLGVFICIRCAGIHRNLGVHISKVRSVNLDSW 77

  Fly    79 TPEQVISLQQMGNSRARAVYEAQLPDGFRRPQTDTALENFIRAKYEHKKYLAREWVPPSPPKVDW 143
            |||||.:::.|||.:||.|||..||..||||..|..:|.|||:|||.|:|:.|::|   .|:||
 Worm    78 TPEQVQTMRVMGNEKARQVYEHDLPAQFRRPTNDQQMEQFIRSKYEQKRYILRDFV---YPRVD- 138

  Fly   144 AKEIDEELERQKRKKKSTQAQATLGLAGVAGGSGDKRLSGSSASALKNTPLPAPLPKPKPNQVGG 208
            |.::.:.|. |.:||..|   ..:.:|.....|.:...:.|:|:|     .|:.|....|
 Worm   139 ASQLPKSLS-QAQKKVGT---PVVNIASRGSSSSNGHSTASAAAA-----APSLLDFSDP----- 189

  Fly   209 CSPKTTQRVQLNSSGVSSAGESDLLGLSSPTKPIVATNASQDLQNESFTSFLSAESIAGQPDKPI 273
              |.:|...:   ..|:...:.|.|.| .|..|..|..|..| ..:.|.||:||.|...|.:...
 Worm   190 --PASTTPAK---KAVNLFDDFDGLSL-GPAAPAAAPAALND-DFDDFGSFVSANSQNAQQNAQS 247

  Fly   274 GSNGDAANLMGSKPNSLAQEE------QDFFNQGSLGAGGNEKDQSGKMSKDSILALYGSAPATH 332
            ...|.|.  ..|.|.:.|...      .|.....|.....|..||  |.:...||:|:|.:....
 Worm   248 LGGGFAD--FSSAPTTAAAAPSASSGLDDLTALSSTAPATNGSDQ--KKTNADILSLFGPSGGIS 308

  Fly   333 NPQMNFGGFTGMAPGGYMH---QQQQQQIPHQ---------------------------FMTPPN 367
            .|.:       :||||:..   |....|||.|                           |..||.
 Worm   309 APNV-------VAPGGFAGFGLQAAPAQIPQQASSFHQFGAPAPAPQQNDMFGGLSGINFGAPPP 366

  Fly   368 SVSMYNSPVMAAPNAFSNAAISSATAMSMGGSHGFTGAQFPS--TGGSPYAAAG----------- 419
            |..|...|.||.|..|..|...   |||   |.||.|....|  |..||..:.|
 Worm   367 SAQMSQIPPMAPPQYFGAAQFG---AMS---SSGFGGMSMQSKPTPTSPTGSQGFNIPNKSNAFA 425

  Fly   420 QAAATNLMQTNQSILSGMPLFGAVPQQQQQHQQQLQQQHHPQLGGLSMNLMQPLPSGLNIGQPPQ 484
            ..|...:|:||         :|             |...|.|...:|.|...|:|:..|......
 Worm   426 DLALGKVMKTN---------YG-------------QSAIHHQAAPISSNRASPMPAQSNTAANND 468

  Fly   485 GAGGFAATGP--TTSSVPSNLNQQFG 508
            ....||:..|  |.:|..|.|:...|
 Worm   469 LFDMFASAPPPVTVNSSSSGLDDLLG 494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8243	NP_610424.1	ArfGap	18..132	CDD:279720	74/113 (65%)
		COG5347	20..300	CDD:227651	116/285 (41%)
W09D10.1	NP_499364.1	ArfGap_SMAP	20..122	CDD:350068	68/101 (67%)
		DEC-1_N	<301..>415	CDD:368028	33/126 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	168	1.000	Domainoid score	I2326
eggNOG	1	0.900	-	-		E1_COG5347
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	203	1.000	Inparanoid score	I2450
Isobase	1	0.950	-	0	Normalized mean entropy	S2206
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001773
OrthoInspector	1	1.000	-	-		oto19666
orthoMCL	1	0.900	-	-		OOG6_100831
Panther	1	1.100	-	-	LDO	PTHR45705
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1895
SonicParanoid	1	1.000	-	-		X1301
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	11.930