Protein Alignment CG8243 and Asap1

DIOPT Version :9

• Sequence 1: NP_610424.1
• Gene: CG8243 / 35890
• FlyBaseID: FBgn0033349
• Length: 517
• Species: Drosophila melanogaster
• Sequence 2: XP_006520455.1
• Gene: Asap1 / 13196
• MGIID: 1342335
• Length: 1223
• Species: Mus musculus
• Alignment Length: 535
• Identity: 128/535 - (23%)
• Similarity: 203/535 - (37%)
• Gaps: 131/535 - (24%)

  Fly    10 TKLIQEKCQTLLTQMLRDEDNKYCVDCDAKGPRWASWNLGMFLCIRCAGIHRNLGVHISRVKSVN 74
            ||.|.|..|.|       ..|..|.||.:..|.|.|.|||:..||.|:||||.:||||||::|:.
Mouse   529 TKAIIEDVQRL-------PGNDICCDCGSSEPTWLSTNLGILTCIECSGIHREMGVHISRIQSLE 586

  Fly    75 LDTWTPEQVISLQQMGNSRARAVYEAQLPDGFRRPQTD---TALENFIRAKY-EHKKYLAREWVP 135
            ||.....:::..:.:||:....:.||.||....:|...   |..:.:|.||| :|:  .:|:...
Mouse   587 LDKLGTSELLLAKNVGNNSFNDIMEANLPSPSPKPTPSSDMTVRKEYITAKYVDHR--FSRKTCA 649

  Fly   136 PSPPKVDWAKEIDEELERQKRKKKSTQAQATLGLAGVAGGSGDKRLSGSSASALKNTPLPAPLPK 200
            .|..|      ::|.||       :.:::..|.|..|..               :...|..||.:
Mouse   650 SSSAK------LNELLE-------AIKSRDLLALIQVYA---------------EGVELMEPLLE 686

  Fly   201 PKPNQVGGCSPKTTQRVQLNSSGVSSAGESDLLGLSSPTKPIVATNASQDLQNESFTSFLSAESI 265
            | ..::|    :|...:.:.::..:|....|.|         |....:.|.|.....:.|...|:
Mouse   687 P-GQELG----ETALHLAVRTADQTSLHLVDFL---------VQNCGNLDKQTSVGNTVLHYCSM 737

  Fly   266 AGQPD--------KP----IGSNGDAANLMGSKPNSLAQEEQDFFNQGSLGAGGNEKDQSGKMSK 318
            .|:|:        ||    :..||:.|  :.......|.:.:|..:|.          :|||.:
Mouse   738 YGKPECLKLLLRSKPTVDIVNQNGETA--LDIAKRLKATQCEDLLSQA----------KSGKFN- 789

  Fly   319 DSILALYGSAPATH-NPQMNFGGFTGMAPGGYMHQQQQQQIPHQFMTPPNSVSMYNSPVMAAPNA 382
                      |..| ..:.|            :.|.:..:........|:.:....||   .|.:
Mouse   790 ----------PHVHVEYEWN------------LRQDEMDESDDDLDDKPSPIKKERSP---RPQS 829

  Fly   383 F-SNAAISSATAMSMGG----------SHG-FTGAQFPSTG----GSPYAAAGQAAATNLMQTNQ 431
            | .:::||....:::.|          |:| ||...|.||.    .||.:.|......|..:...
Mouse   830 FCHSSSISPQDKLALPGFSTPRDKQRLSYGAFTNQIFASTSTDLPTSPTSEAPPLPPRNAGKGPT 894

  Fly   432 SILSGMPLFGAVPQQQQQHQQQLQQQHHPQLGGLSMNLMQPLPSGLNIGQPPQGAGGFA-ATGPT 495
            ...|.:|| |.  |.........:::..|...|....|..| ||.|..|.|.:||..:. ..||.
Mouse   895 GPPSTLPL-GT--QTSSGSSTLSKKRPPPPPPGHKRTLSDP-PSPLPHGPPNKGAIPWGNDVGPL 955

  Fly   496 TSSVPSN----LNQQ 506
            :||..:|    |:||
Mouse   956 SSSKTANKFEGLSQQ 970

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8243	NP_610424.1	ArfGap	18..132	CDD:279720	41/117 (35%)
		COG5347	20..300	CDD:227651	72/295 (24%)
Asap1	XP_006520455.1	BAR_ASAP1	138..344	CDD:153325
		PH_ASAP	407..513	CDD:270071
		ArfGap_ASAP1	528..649	CDD:350073	46/128 (36%)
		ANK repeat	692..725	CDD:293786	7/45 (16%)
		Ank_2	696..>768	CDD:372319	15/82 (18%)
		ANK repeat	727..758	CDD:293786	6/30 (20%)
		Atrophin-1	845..>1109	CDD:367360	36/130 (28%)
		SH3_ASAP1	1165..1221	CDD:212898

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5347
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810