DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8243 and ADAP1

DIOPT Version :9

Sequence 1:	NP_610424.1	Gene:	CG8243 / 35890	FlyBaseID:	FBgn0033349	Length:	517	Species:	Drosophila melanogaster
Sequence 2:	NP_001271237.1	Gene:	ADAP1 / 11033	HGNCID:	16486	Length:	385	Species:	Homo sapiens

Alignment Length:	129	Identity:	48/129 - (37%)
Similarity:	71/129 - (55%)	Gaps:	25/129 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 YCVD--------------CDAKG-------PRWASWNLGMFLCIRCAGIHRNLGVHISRVKSVNL 75
            ||::              |..:|       |.|||:.||:|:|:.|:|||||: ..:|:||||.|
Human    10 YCINPARRKWKEFEKMLGCAEEGHASLGRDPDWASYTLGVFICLSCSGIHRNI-PQVSKVKSVRL 73

  Fly    76 DTWTPEQVISLQQMGNSRARAVYEAQLPDGFRRP-QTDTAL--ENFIRAKYEHKKYLAREWVPP 136
            |.|...||..:...||..|||.:|:::|..:.|| .:|..|  |.:||||||.::::..|...|
Human    74 DAWEEAQVEFMASHGNDAARARFESKVPSFYYRPTPSDCQLLREQWIRAKYERQEFIYPEKQEP 137

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8243	NP_610424.1	ArfGap	18..132	CDD:279720	46/123 (37%)
CG8243	NP_610424.1	COG5347	20..300	CDD:227651	48/129 (37%)
ADAP1	NP_001271237.1	ArfGap	28..137	CDD:214518	45/109 (41%)
		PH1_ADAP	141..249	CDD:270072
		PH	142..239	CDD:278594
		PH2_ADAP	263..368	CDD:241282
		PH	266..366	CDD:278594
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5347
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810