DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8243 and adap2

DIOPT Version :9

Sequence 1:	NP_610424.1	Gene:	CG8243 / 35890	FlyBaseID:	FBgn0033349	Length:	517	Species:	Drosophila melanogaster
Sequence 2:	XP_021329475.1	Gene:	adap2 / 100331455	ZFINID:	ZDB-GENE-070912-21	Length:	418	Species:	Danio rerio

Alignment Length:	150	Identity:	55/150 - (36%)
Similarity:	81/150 - (54%)	Gaps:	10/150 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 QEKCQTLLTQMLRDEDNKYCVDCDAKGPRWASWNLGMFLCIRCAGIHRNLGVHISRVKSVNLDTW 78
            :||.:.:|.::::..:|..|.||.|..|.|||..||:|:|:.|:|.||||.. |||:||:.||.|
Zfish     4 REKNKKILLELVKLPENNCCADCGAADPDWASCKLGIFVCLTCSGTHRNLPT-ISRIKSIRLDFW 67

  Fly    79 TPEQVISLQQMGNSRARAVYEAQLPDGFRRP---QTDTALENFIRAKYEHKKYLAREWVPPSPPK 140
            ..|.|..::..||..|:..||..:|..:.||   ..:...|.:||||||..::...:...|....
Zfish    68 DDELVQFMKANGNCSAKNFYEKCVPVFYYRPHPHDCEVLREQWIRAKYERMEFTEEKTERPYTAD 132

  Fly   141 VD----WAKEID--EELERQ 154
            |.    |.|..|  :.|||:
Zfish   133 VYEGMLWKKGRDNGQFLERK 152

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8243	NP_610424.1	ArfGap	18..132	CDD:279720	45/116 (39%)
CG8243	NP_610424.1	COG5347	20..300	CDD:227651	53/143 (37%)
adap2	XP_021329475.1	ArfGap	8..123	CDD:307528	45/115 (39%)
		PH1_ADAP	134..240	CDD:270072	6/18 (33%)
		PH2_ADAP	254..361	CDD:241282
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910