DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG8243 and acap3b

DIOPT Version :9

Sequence 1:NP_610424.1 Gene:CG8243 / 35890 FlyBaseID:FBgn0033349 Length:517 Species:Drosophila melanogaster
Sequence 2:NP_001076484.1 Gene:acap3b / 100009646 ZFINID:ZDB-GENE-070209-274 Length:846 Species:Danio rerio


Alignment Length:398 Identity:91/398 - (22%)
Similarity:156/398 - (39%) Gaps:109/398 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly    30 NKYCVDCDAKGPRWASWNLGMFLCIRCAGIHRNLGVHISRVKSVNLDTWTPEQVISLQQMGNSRA 94
            |:.|.||....|||||.|||:.|||.|:||||:||||.|:|:|:.||||.||.:..:.::||:..
Zfish   415 NEICCDCGQSDPRWASINLGILLCIECSGIHRSLGVHCSKVRSLTLDTWEPELMKLMCELGNTVI 479

  Fly    95 RAVYEAQLPD-GFRRPQTDTA---LENFIRAKYEHKKYL---------------AREWVPPSPPK 140
            ..:||....: |.::|..:::   .|.:|:|||..:|:|               :..|      .
Zfish   480 NQIYEGACEEQGLKKPGPNSSRQEKEAWIKAKYVERKFLKKMCGSEALLEGGRKSHHW------S 538

  Fly   141 VDWAKEIDEELERQKRKKKSTQAQATLGLAGVAGGSGDKRLSGSSASALKNTPLPAPLPKPKPNQ 205
            |...:..:..:...|.::|.....|.:....::..:...:....|...              |::
Zfish   539 VKKCRRHNSSIRAPKTRRKYRHDAAIMSPGNLSAAAAAAKFRRESLFC--------------PDE 589

  Fly   206 VG--------GCSPKTTQRVQLNSS-GVSSAGESDLLGLSSPTKPIVATNASQDLQNESFTS-FL 260
            :.        |..|::...:..:|. |.|:.|.:|:|...|    :|.:...::.::...:| .:
Zfish   590 LDSLFSYFDTGSGPRSPAGLSSDSGLGGSTDGSTDILVFGS----VVDSVTEEECEDSDESSGEV 650

  Fly   261 SAESIAGQPDKPIGSNGDAANLM------------------GSKPNSLAQEEQ------DFFNQG 301
            ..|..|..|:.  |...|...|:                  |:..||:::|::      .....|
Zfish   651 DIEQEASDPED--GRELDPNTLLHKASRARNMPVMAEALAHGADVNSVSEEDESKSPLIQAVTGG 713

  Fly   302 SL---------GAGGNEKDQSGKMSKDSILALYGSAPATHNPQMNFGGFTGMA------PGGYMH 351
            ||         ||..|::|            :.|..|..|...:   |.||..      ..|.|.
Zfish   714 SLIACEFLLQNGADVNQRD------------IRGRGPLHHATCL---GHTGQVCLFLKRGAGQME 763

  Fly   352 QQQQQQIP 359
            ..:..|.|
Zfish   764 VDEDGQDP 771

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG8243NP_610424.1 ArfGap 18..132 CDD:279720 46/120 (38%)
COG5347 20..300 CDD:227651 74/322 (23%)
acap3bNP_001076484.1 BAR_ACAP3 16..215 CDD:153321
PH 269..363 CDD:278594
PH_ACAP 271..367 CDD:270070
ArfGap 403..520 CDD:279720 46/104 (44%)
ANK repeat 666..697 CDD:293786 5/30 (17%)
ANK 668..787 CDD:238125 22/119 (18%)
Ank_2 671..759 CDD:289560 17/102 (17%)
ANK repeat 699..732 CDD:293786 7/32 (22%)
ANK repeat 734..759 CDD:293786 6/27 (22%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.910

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