DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG8243 and LOC100005008

DIOPT Version :9

Sequence 1:NP_610424.1 Gene:CG8243 / 35890 FlyBaseID:FBgn0033349 Length:517 Species:Drosophila melanogaster
Sequence 2:XP_001344168.4 Gene:LOC100005008 / 100005008 -ID:- Length:958 Species:Danio rerio


Alignment Length:175 Identity:55/175 - (31%)
Similarity:73/175 - (41%) Gaps:33/175 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly    30 NKYCVDCDAKGPRWASWNLGMFLCIRCAGIHRNLGVHISRVKSVNLD--TWTPEQVISLQQM-GN 91
            ||.|.||.|..|.|||.||.:.:|..|||.||::|...|:|:.:.||  .|| |.:|.|..: ||
Zfish   398 NKVCADCGAANPEWASVNLLVVICEACAGAHRSMGSSRSKVRGLKLDDKVWT-EPLIQLFVLHGN 461

  Fly    92 SRARAVYEAQLPDGFRRPQT---------DTALENFIRAKYEHKKYLAREWVPPSPPKVDWAKEI 147
            ..|..|:      |...|.|         |...| ||.|||....|.....:..|...:|     
Zfish   462 KTANNVW------GHNIPPTEQISPLASPDQRAE-FILAKYHKGLYRKAHPLAASQKLLD----- 514

  Fly   148 DEELERQKRKKKSTQAQATLGL----AGVAGGSGDKRLSGSSASA 188
                :|.:........:.|:.|    |.|:..|.|..|..:.|.|
Zfish   515 ----QRLREVVCGPAVEETVSLLCSGAKVSCSSSDPELKSAIAVA 555

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG8243NP_610424.1 ArfGap 18..132 CDD:279720 43/113 (38%)
COG5347 20..300 CDD:227651 55/175 (31%)
LOC100005008XP_001344168.4 PH-like 291..375 CDD:302622
PH 292..380 CDD:278594
ArfGap 386..503 CDD:279720 43/112 (38%)
RhoGAP 769..939 CDD:295372
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5347
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.810

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