Protein Alignment Spt and Vinac1

DIOPT Version :10

• Sequence 1: NP_610423.3
• Gene: Spt / 35889
• FlyBaseID: FBgn0033348
• Length: 591
• Species: Drosophila melanogaster
• Sequence 2: XP_001004454.2
• Gene: Vinac1 / 668894
• MGIID: 3649276
• Length: 1413
• Species: Mus musculus
• Alignment Length: 669
• Identity: 132/669 - (19%)
• Similarity: 220/669 - (32%)
• Gaps: 216/669 - (32%)

  Fly    33 LLEFATLA-----------HSSFCSQGQSECSELVCLCLSQIMICIRQVENTMKLECGTTVSVSH 86
            |.|.:|||           ||:  :.|..|.          :.:..:|.:.|.:...|.......
Mouse   738 LQEVSTLAPSIIDLARKEVHSA--NTGSEEL----------LRVSFQQSQGTREDRWGLVARAGD 790

  Fly    87 QYFLDRIRWCLKRLMH-LYSEESSSEAVAPERSFLKLVDGALDCLAQFTSHS------EENTDTS 144
            .|.|     |.:...| |.:|...|.|     :|::|... |..:.|..:.|      ::|.|..
Mouse   791 WYPL-----CQQLFCHNLETELPGSMA-----AFVELQQD-LALMVQVAAKSGPVNVDKKNPDLM 844

  Fly   145 NCPKTPKEVLPLSQKLRANIDLILGQSLGFANVALSQDKRALSALCQKVIRECN----------A 199
            ..|:...|:...|:|...:...:|.|       .||.|     .|.:..:||.|          |
Mouse   845 GHPRLLLELQDRSEKTEIHAKQLLDQ-------VLSSD-----GLQEPTLREENIDNGCLLWAVA 897

  Fly   200 FQE--ECKESFSANY-LSTLKLR-AMTMEQAIY-------QLEDFINDALLRLVFTCFLDFEKFS 253
            .|:  :|.|.||... |..|.|| |:..:|.:.       ::...:.:|.
Mouse   898 VQDLMQCMERFSRRQGLFLLPLRQAVKNQQGLQKGLGQAAEISQRLQEAA--------------- 947

  Fly   254 VDKIRALLRNSPDNDDLADEFIADFDVNIDRATQIGIFAISF---APNLKMKTIMRSCLASFESL 315
              |:.::|...............:..|..|...::....:|.   .|:|..:         ||.|
Mouse   948 --KLSSVLCGDAQVKGEISFLCREVHVLTDALLEVAHILVSSPKPCPSLSTR---------FELL 1001

  Fly   316 DTTLIPSLQAHGSDLHSDILEQHFNEEVAKFKAALQEIIDSRALVGCCLEILTSGISATEKLFDK 380
            ...|         .|.:..|..:.....|.::...|::|...:...  :|.:.|.|.|.:.:...
Mouse  1002 CLEL---------SLRAKALTDYLTSINAAYEHMFQDVISKSSQNR--IEGMLSTIQAVQGIIAG 1055

  Fly   381 QRLEDLVQ----ISLLLVEHFQLEVNRK--GLSETQ-----DRLGEEYYQQFIRVLRECKAILMC 434
            .:..:.||    :||..:.....||.||  .|.|.|     |.|..|:..:....:.:.:|:.
Mouse  1056 GQESETVQKDLLVSLESILTLTKEVVRKVPVLQEVQSLHTLDWLQWEWAAKVHHAVTQLQALE-- 1118

  Fly   435 ASQVEPQRILKRFKILRTILRKLHGSLGAGKQ----EEELPIPLAPLLADDTKGVNE-------- 487
            .|.:|..|:|.::...|            |:|    ||:|..| .|...:.|.|...
Mouse  1119 GSHMEAWRLLVQYLKPR------------GEQAKPLEEDLVQP-PPHCNEGTAGTTSGVSVDSQG 1170

  Fly   488 ---------------DETHFTGYKTA-----RSGSILY-------------DTERRNRVTRRTDN 519
                           ||...|...||     :|||:..             ..:..||:|:.| .
Mouse  1171 AVPKDTPESSVGTCADEPATTRTTTADRSMHQSGSLSLPPAQMDQPAPEDSSADSENRITQIT-Q 1234

  Fly   520 KLPTNTLDIKSDKAKPHGNVLRRESLR---TVMFKRQNIAESRKLYTS--------------MSN 567
            ::.|..|             |...|||   .|:.|.|.||.:||:..|              ..:
Mouse  1235 EMATEVL-------------LMARSLRKSGQVLTKDQLIASARKVSASGKDFTRLIHIIAKNCID 1286

  Fly   568 QSTDLQITDILDQLTGMSN 586
            |....::..:::|:..||:
Mouse  1287 QRCSQELLCMVEQIQTMSS 1305

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spt	NP_610423.3	Serendipity_A	1..468	CDD:368466	95/491 (19%)
Vinac1	XP_001004454.2	Vinculin	15..>610	CDD:460040
		Vinculin	<1224..1375	CDD:460040	22/96 (23%)