Protein Alignment Spt and ctnna1

DIOPT Version :10

• Sequence 1: NP_610423.3
• Gene: Spt / 35889
• FlyBaseID: FBgn0033348
• Length: 591
• Species: Drosophila melanogaster
• Sequence 2: NP_571531.1
• Gene: ctnna1 / 30741
• ZFINID: ZDB-GENE-991207-24
• Length: 907
• Species: Danio rerio
• Alignment Length: 687
• Identity: 117/687 - (17%)
• Similarity: 255/687 - (37%)
• Gaps: 176/687 - (25%)

  Fly     9 EACLLILNRNNAAAANWLNDLCAVLLEFATLAHSSFCSQGQSECSELVCLCLSQIMICIRQV-EN 72
            :.|..:...|...||..|......||..|.:|.                  :.|:::.::.| ||
Zfish   114 DPCSSVKRGNMVRAARALLSAVTHLLVLADMAD------------------VYQLLLQLKLVEEN 160

  Fly    73 TMKL-ECGTTVSVSHQY-----FLDRIRWCLKRLMHLYSEESSSEAVAPERSFLK-----LVDGA 126
            .||: ..||...:..||     .:|::.....:......:....:.:|..|..|:     |...:
Zfish   161 LMKVRNAGTEQDLGIQYKALKPEVDKLNMMAAKRQQELKDVHHKDQMAAARGVLQRNVPMLYTAS 225

  Fly   127 LDCL-----------------------------AQFTSHSEENTDTSNC---------PKTPKEV 153
            ..||                             ||.|| ||:::.:...         ....|::
Zfish   226 RACLQHPDVAAYKANRDLIYKQLQHAVSGISNAAQATS-SEDSSFSQTAGGGELAYALNNFDKQI 289

  Fly   154 L--PLS---QKLRANID-----LILGQSLGFANVALSQDKRALSALCQKVIRECNAFQEECKESF 208
            :  |||   ::.|.:::     :|.|.:| .|:.:.::|.|.     ::::.|||:.::..::..
Zfish   290 IVDPLSFSEERFRPSLEERLESIISGAAL-MADSSCTRDDRR-----ERIVAECNSVRQALQDLL 348

  Fly   209 SANYLSTL--KLRAMTMEQAIYQLEDFINDALLRLVFTCFLD-----FEKFSVDKIRALLRNSPD 266
            | .|:...  |.::..:..||.::.....| |.|.:....:|     |.:.:|..:..:......
Zfish   349 S-EYMGNAGRKEKSDALNTAIDRMTKKTRD-LRRQLRKAVMDHVSDSFLETNVPLLVLIEAAKNG 411

  Fly   267 NDDLADEFIADFDVNIDRATQIGIFAISFAPNLKMKTIMRSCLASFESLDTTLIPSLQAHGSDLH 331
            |:....|:...|..:.::..::...|.|.:.|.:...::|...:..|:|...:|.:..|..:..:
Zfish   412 NEKEVKEYAQVFREHANKLIEVANLACSISNNEEGVKLVRMAASQLETLCPQVINAALALAAKPN 476

  Fly   332 SDILEQH---FNEEVAKFKAALQEIIDSRALVGCCLEILTSGISATEKLFDKQRLEDLVQISLLL 393
            |.:.:.:   |.::..|....|.:.:|.          :||             ::|.:.:|
Zfish   477 SKVAQDNMDLFKDQWEKQVRVLTDAVDD----------ITS-------------IDDFLCVS--- 515

  Fly   394 VEHFQLEVNRKGLS-ETQDRLGEEYYQQFIRVLRECKAILMCASQVE-------PQRILKRFKIL 450
            ..|...:||:..:: :.:|..|.:.....||. |..:.:.:..|:::       .:::|:..|:|
Zfish   516 ENHILEDVNKCVIALQEKDVDGLDRTAGAIRG-RAARVVHVVTSEMDNYMPGVYTEKVLEATKLL 579

  Fly   451 -RTILRKLHGSLGAGKQEEELPIPLAPLLADDTKGVNEDE------THFTGYKTARSGSILYDTE 508
             .|::.:.         .|::...:..|.|::.:.|:|:|      ..:.|.:..|...::..|.
Zfish   580 TETVMPRF---------TEQVEAAVEALSANNGQPVDENEFIDASRLVYDGVRDIRKAVLMIRTP 635

  Fly   509 RRNRVTRRTDNKLPTNTLDIKSDKA--KPHGNVLRRESLRTVMF-----KRQNIA--------ES 558
            .     ...|:...|...|.:|..:  .....::..:|.|.:|.     ::..||        |.
Zfish   636 E-----ELDDSDFETEDFDSRSRTSVQTEDDQLIAGQSARAIMAQLPQEQKAKIAEQVASFQEEK 695

  Fly   559 RKLYTSMS---NQSTDL-----QITDILDQLTGMSNG 587
            .||...:|   :...|:     |:..|:.::|..:.|
Zfish   696 SKLDAEVSKWDDSGNDIIVLAKQMCMIMMEMTDFTRG 732

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spt	NP_610423.3	Serendipity_A	1..468	CDD:368466	90/537 (17%)
ctnna1	NP_571531.1	Vinculin	19..867	CDD:460040	117/687 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	870..895